ArticleMolecular genetics and genomics : MGG2005
Large deletions within the first intron in VRN-1 are associated with spring growth habit in barley and wheat.
Article in Molecular genetics and genomics : MGG, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 295 papers.
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295 citing papers in PubMed, 686 citations in OpenAlex.
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- MicroRNA156 and its targeted SPL genes interact with the photoperiod, vernalization, and gibberellin pathways to regulate wheat heading time.The Plant journal : for cell and molecular biology · 2026Article
- Association mapping of wheat distinctness, uniformity, and stability traits identifies evidence ofFrontiers in plant science · 2026Article
- Genomic prediction models for morpho-phenological traits in durum wheat based on Vrn, Ppd, and Rht alleles.The plant genome · 2025Article
- Fine tuning wheat heading time through genome editing of transcription factor binding sites in Ppd-1 gene promoter.Scientific reports · 2025Article
- The FKF1-ELF3-PRC2 module regulates flowering time in response to light in temperate grasses.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Ambient temperature influenced co-expression network of major developmental, circadian, and photoreceptor genes in bread wheat.Scientific reports · 2025Article
- A naturally occurring SNP modulates thermotolerance divergence among grapevines.Nature communications · 2025Article
- Allelic Variations in Phenology Genes in Club Wheat (International journal of molecular sciences · 2025Article
- Identification and validation of a major quantitative trait locus for precise control of heading date in wheat (Triticum aestivum L.).BMC plant biology · 2025Article
235 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The broad adaptability of wheat and barley is in part attributable to their flexible growth habit, in that spring forms have recurrently evolved from the ancestral winter growth habit. In diploid wheat and barley growth habit is determined by allelic variation at the VRN-1 and/or VRN-2 loci, whereas in the polyploid wheat species it is determined primarily by allelic variation at VRN-1. Dominant Vrn-A1 alleles for spring growth habit are frequently associated with mutations in the promoter region in diploid wheat and in the A genome of common wheat. However, several dominant Vrn-A1, Vrn-B1, Vrn-D1 (common wheat) and Vrn-H1 (barley) alleles show no polymorphisms in the promoter region relative to their respective recessive alleles. In this study, we sequenced the complete VRN-1 gene from these accessions and found that all of them have large deletions within the first intron, which overlap in a 4-kb region. Furthermore, a 2.8-kb segment within the 4-kb region showed high sequence conservation among the different recessive alleles. PCR markers for these deletions showed that similar deletions were present in all the accessions with known Vrn-B1 and Vrn-D1 alleles, and in 51 hexaploid spring wheat accessions previously shown to have no polymorphisms in the VRN-A1 promoter region. Twenty-four tetraploid wheat accessions had a similar deletion in VRN-A1 intron 1. We hypothesize that the 2.8-kb conserved region includes regulatory elements important for the vernalization requirement. Epistatic interactions between VRN-H2 and the VRN-H1 allele with the intron 1 deletion suggest that the deleted region may include a recognition site for the flowering repression mediated by the product of the VRN-H2 gene of barley.
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