ArticleThe European physical journal. E, Soft matter2005
Structural investigations of DNA-polycation complexes.
Article in The European physical journal. E, Soft matter, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 128 citations in OpenAlex.
- Structural Dynamics of Peptiplexes Formed between Cationic Cell-Penetrating Peptides and DNA: A Comparative Study on TAT-HIV and NLS-SV40T.ACS applied bio materials · 2026Article
- Synthetic polypeptides inhibit nucleic acid-induced inflammation in autoimmune diseases by disrupting multivalent TLR9 binding to LL37-DNA bundles.Nature nanotechnology · 2024Article
- Re-examination of Peptide-Sequence-Dependent Gene Expression of Cysteine-Installed Pegylated Oligolysine/DNA Complexes.ACS omega · 2022Article
- Structural Polymorphism of Single pDNA Condensates Elicited by Cationic Block Polyelectrolytes.Polymers · 2020Review
- Pressurized DNA state inside herpes capsids-A novel antiviral target.PLoS pathogens · 2020Article
- CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis.Nature communications · 2019Article
- Modulation of toll-like receptor signaling by antimicrobial peptides.Seminars in cell & developmental biology · 2019Review
- Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9.Nature communications · 2019Article
- Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors.Scientific reports · 2018Article
- Crystallinity of Double-Stranded RNA-Antimicrobial Peptide Complexes Modulates Toll-Like Receptor 3-Mediated Inflammation.ACS nano · 2017Article
- Tuning DNA Condensation with Zwitterionic Polyamidoamine (zPAMAM) Dendrimers.Macromolecules · 2017Article
- Shape and Interhelical Spacing of DNA Origami Nanostructures Studied by Small-Angle X-ray Scattering.Nano letters · 2016Article
- A review of immune amplification via ligand clustering by self-assembled liquid-crystalline DNA complexes.Advances in colloid and interface science · 2016Review
- Liquid-crystalline ordering of antimicrobial peptide-DNA complexes controls TLR9 activation.Nature materials · 2015Article
- A histone-like protein induces plasmid DNA to form liquid crystals in vitro and gene compaction in vivo.International journal of molecular sciences · 2013Article
- A comparison of DNA compaction by arginine and lysine peptides: a physical basis for arginine rich protamines.Biochemistry · 2013Article
- A novel assay for quantifying the number of plasmids encapsulated by polymer nanoparticles.Small (Weinheim an der Bergstrasse, Germany) · 2012Article
- Role of amino acid insertions on intermolecular forces between arginine peptide condensed DNA helices: implications for protamine-DNA packaging in sperm.The Journal of biological chemistry · 2011Article
- Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery.Nature materials · 2011Article
- Charge inversion, condensation and decondensation of DNA and polystyrene sulfonate by polyethylenimine.The European physical journal. E, Soft matter · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The internal structure of DNA-polycation complexes is investigated by synchrotron small-angle X-ray scattering (SAXS). Hexagonal packing of DNA is observed for DNA complexed with poly-L-lysine (PL), poly-L-arginine (PA), spermine (Sp), and linear and branched polyethyleneimine (lPEI and bPEI, respectively). Variations in the internal spacings and degree of long-range ordering are dependent on both polycation type and concentration of added salt. With increasing concentration of monovalent salt, a discontinuous phase transition is observed from compact to loose bundles and finally to an isotropic network phase. This salt-induced melting transition was found to be universal for all polyplexes studied and is in quantitative agreement with a simple free energy model based solely on electrostatic and entropic contributions. Using the osmotic stress method, bulk modulus (K) is measured for PL-DNA and PA-DNA polyplexes at various salt concentrations. With increasing osmotic force, we show that the salt-induced melting transition is shifted and compression in the loose bundle regime is in qualitative agreement with our model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.