Evidence map›Paper›PMID 15687294›Full record

ArticleGenome research2005

Mapping segmental and sequence variations among laboratory mice using BAC array CGH.

Antoine M Snijders, Norma J Nowak, Bing Huey, Jane Fridlyand, Sindy Law, Jeffrey Conroy, Taku Tokuyasu, Kubilay Demir, Readman Chiu, Jian-Hua Mao and 5 more

Abstract read
In one paragraph

Article in Genome research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
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  7. Online resources for genomic structural variation.Methods in molecular biology (Clifton, N.J.) · 2012
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  20. Extensive genomic copy number variation in embryonic stem cells.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Antoine M SnijdersCancer Research Institute, University of California San Francisco, San Francisco, California 94143, USA.
Norma J Nowak
Bing Huey
Jane Fridlyand
Sindy Law
Jeffrey Conroy
Taku Tokuyasu
Kubilay Demir
Readman Chiu
Jian-Hua Mao
Ajay N Jain
Steven J M Jones
Allan Balmain
Daniel Pinkel
Donna G Albertson

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
MICROARRAY BASED SCANNING OF THE MOUSE GENOMEU01CA084118 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALBERTSON, DONNA G · 1999 to 2008
$3.9M
NCI NIH HHS CA84118NCI NIH HHS P02137165CNNCI NIH HHS P30 CA016056NCI NIH HHS P30 CA16056NCI NIH HHS U01 CA084118
6 · The paper itself

Abstract

We used arrays of 2069 BACs (1303 nonredundant autosomal clones) to map sequence variation among Mus spretus (SPRET/Ei and SPRET/Glasgow) and Mus musculus (C3H/HeJ, BALB/cJ, 129/J, DBA/2J, NIH, FVB/N, and C57BL/6) strains. We identified 80 clones representing 74 autosomal loci of copy number variation (|log(2)ratio| >/= 0.4). These variant loci distinguish laboratory strains. By FISH mapping, we determined that 63 BACs mapped to a single site on C57BL/6J chromosomes, while 17 clones mapped to multiple chromosomes (n = 16) or multiple sites on one chromosome (n = 1). We also show that small ratio changes (Delta log(2)ratio approximately 0.1) distinguish homozygous and heterozygous regions of the genome in interspecific backcross mice, providing an efficient method for genotyping progeny of backcrosses.

Indexed as

GenomeAnimalsChromosome MappingChromosomes, Artificial, BacterialCrosses, GeneticGene DosageGenetic MarkersGenetic VariationMiceMice, Inbred BALB CMice, Inbred C3HMice, Inbred C57BLMice, Inbred DBAMice, Inbred StrainsNucleic Acid HybridizationOligonucleotide Array Sequence AnalysisGenetic Markers

Identifiers

PMID15687294
PMCPMC546532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.