Evidence map›Paper›PMID 15687293›Full record

ArticleGenome research2005

Pooled genomic indexing of rhesus macaque.

Aleksandar Milosavljevic, Ronald A Harris, Erica J Sodergren, Andrew R Jackson, Ken J Kalafus, Anne Hodgson, Andrew Cree, Weilie Dai, Miklos Csuros, Baoli Zhu and 3 more

Abstract readComparative Study
In one paragraph

Article in Genome research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Aleksandar MilosavljevicHuman Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
Ronald A Harris
Erica J Sodergren
Andrew R Jackson
Ken J Kalafus
Anne Hodgson
Andrew Cree
Weilie Dai
Miklos Csuros
Baoli Zhu
Pieter J de Jong
George M Weinstock
Richard A Gibbs

Funding

CONTINUING MEGABASE SEQUENCING AT THE BCM HGSCU54HG002051 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A · 1999 to 2003
$91.1M
Clone-Array Pooled Shotgun IndexingR01HG002583 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI MILOSAVLJEVIC, ALEKSANDAR · 2002 to 2004
$1.5M
Clone Pooling Methods for Physical MappingU01RR018464 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI MILOSAVLJEVIC, ALEKSANDAR · 2002 to 2004
$945k
NCRR NIH HHS U01 RR018464NCRR NIH HHS U01 RR 18464NHGRI NIH HHS R01 HG002583NHGRI NIH HHS R01 HG 02583-01NHGRI NIH HHS U54 HG002051NHGRI NIH HHS U54 HG 02051
6 · The paper itself

Abstract

Pooled genomic indexing (PGI) is a method for mapping collections of bacterial artificial chromosome (BAC) clones between species by using a combination of clone pooling and DNA sequencing. PGI has been used to map a total of 3858 BAC clones covering approximately 24% of the rhesus macaque (Macaca mulatta) genome onto 4178 homologous loci in the human genome. A number of intrachromosomal rearrangements were detected by mapping multiple segments within the individual rhesus BACs onto multiple disjoined loci in the human genome. Transversal pooling designs involving shuffled BAC arrays were employed for robust mapping even with modest DNA sequence read coverage. A further innovation, short-tag pooled genomic indexing (ST-PGI), was also introduced to further improve the economy of mapping by sequencing multiple, short, mapable tags within a single sequencing reaction.

Indexed as

GenomeAnimalsChromosome AberrationsChromosomes, Artificial, BacterialContig MappingDNAGenetic MarkersGenome, HumanHumansMacaca mulattaSequence AlignmentSequence Analysis, DNADNAGenetic Markers

Identifiers

PMID15687293
PMCPMC546531

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.