Evidence map›Paper›PMID 15685236›Full record

SynthesisBritish journal of cancer2005

Mechanisms of improved survival from intensive followup in colorectal cancer: a hypothesis.

A G Renehan, M Egger, M P Saunders, S T O'Dwyer

Abstract readMeta-Analysis
In one paragraph

Synthesis in British journal of cancer, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Guideline
  4. Pooled it
  5. Guideline
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Impact of Sensitive Circulating Tumor DNA Monitoring on CT Scan Intervals During Postoperative Colorectal Cancer Surveillance.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  12. Surveillance after curative treatment for colorectal cancer.Nature reviews. Clinical oncology · 2017
    Review
  13. Article
  14. Article
  15. Review
  16. Colorectal cancer surveillance: what's new and what's next.World journal of gastroenterology · 2014
    Review
  17. Article
  18. Towards a personalised approach to aftercare: a review of cancer follow-up in the UK.Journal of cancer survivorship : research and practice · 2011
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A G RenehanDepartment of Surgery, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK. arenehan@picr.man.ac.uk
M Egger
M P Saunders
S T O'Dwyer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A meta-analysis of six randomised trials demonstrated that intensive followup in colorectal cancer was associated with an absolute reduction in all-cause 5-year mortality of 10% (95% confidence interval (CI): 4-16)--however, only two percent (95% CI: 0-5) was attributable to cure from salvage re-operations. We postulate that other factors, such as increased psychological well-being and/or altered lifestyle, and/or improved treatment of coincidental disease may contribute to the remaining lives saved, and form important future research questions.

Indexed as

Follow-Up StudiesColorectal NeoplasmsHumansModels, BiologicalRandomized Controlled Trials as TopicSalvage TherapySurvival Analysis

Identifiers

PMID15685236
PMCPMC2362076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.