ReviewCurrent allergy and asthma reports2005
Exercise-induced bronchoconstriction: pathogenesis.
Review in Current allergy and asthma reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 143 citations in OpenAlex.
- Effect of Creatine Supplementation on the Airways of Youth Elite Soccer Players.Medicine and science in sports and exercise · 2019Trial
- Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Trial
- Cromoglycate, reproterol, or both--what's best for exercise-induced asthma?Sleep & breathing = Schlaf & Atmung · 2012Trial
- Trial
- Prevalence of self-reported asthma among female ice hockey players in the Swedish women's hockey league.Frontiers in sports and active living · 2026Article
- Potential Determinants of Progression from Cough-Variant Asthma to Classic Asthma in Children: Evidence, Mechanisms, and Clinical Research Gaps.Journal of asthma and allergy · 2026Review
- Impact of Physical Exercise on Adult Asthma Control: A Randomized Clinical Trial.Healthcare (Basel, Switzerland) · 2025Article
- Why Every Asthma Patient Tells a Different Story.Journal of clinical medicine · 2025Article
- Circulating Antimicrobial Peptides as Biomarkers of Inflammation and Airway Dysfunction After Marathon Running.Biology · 2025Article
- Exercise-induced bronchoconstriction, allergy and sports in children.Italian journal of pediatrics · 2024Review
- Exercise-Induced Asthma: Managing Respiratory Issues in Athletes.Journal of functional morphology and kinesiology · 2024Review
- Exercise-induced bronchoconstriction assessed by a ratio of surface diaphragm EMG to tidal volume.Physiological reports · 2023Article
- Cross-country skiers often experience respiratory symptoms during and after exercise but have a low prevalence of prolonged cough.BMJ open sport & exercise medicine · 2023Article
- Cold air exposure at - 15 °C induces more airway symptoms and epithelial stress during heavy exercise than rest without aggravated airway constriction.European journal of applied physiology · 2022Article
- Overuse of Short-Acting Beta-2 Agonists (SABAs) in Elite Athletes: Hypotheses to Explain It.Sports (Basel, Switzerland) · 2022Review
- Asthma in elite athletes - do they have Type 2 or non-Type 2 disease? A new insight on the endotypes among elite athletes.Frontiers in allergy · 2022Review
- An Algorithm for Strategic Continuation or Restriction of Asthma Medication Prior to Exercise Challenge Testing in Childhood Exercise Induced Bronchoconstriction.Frontiers in pediatrics · 2022Article
- An experimental exposure study revealing composite airway effects of physical exercise in a subzero environment.International journal of circumpolar health · 2021Article
- Practicing Sport in Cold Environments: Practical Recommendations to Improve Sport Performance and Reduce Negative Health Outcomes.International journal of environmental research and public health · 2021Review
- Predictors of exercise-induced bronchoconstriction in subjects with mild asthma.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is still active debate on the acute mechanism of exercise-induced bronchoconstriction (EIB). Although it is unlikely that vasoconstriction and hyperemia of the bronchial vasculature are essential events for EIB, it is likely that this vasculature enhances the airway response to dehydration and contributes to the pathogenesis of EIB, particularly in elite athletes. Accumulating evidence suggests that airway smooth muscle (ASM) becomes more sensitive as a result of repeated exposure to bulk plasma in response to airway injury from dehydration. Recent evidence also demonstrates sufficient concentrations of mediators that could affect ASM. Paradoxically, mediator release from mast cells may be enhanced and their contractile effects greater when beta(2)-receptor agonists are taken daily. The effect of drugs that have the potential to reduce microvascular leak and reduce or inhibit release or action of these mediators needs to be investigated in elite athletes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.