Evidence map›Paper›PMID 15682477›Full record

Trial reportWorld journal of gastroenterology2005

Helicobacter pylori infection in hemodialysis patients: susceptibility to amoxicillin and clarithromycin.

Selim Aydemir, Sedat Boyacioglu, Gurden Gur, Muge Demirbilek, Fusun-Kamber Can, Murat Korkmaz, Ugur Yilmaz

Open access · hybridAbstract readClinical TrialControlled Clinical Trial
In one paragraph

Trial report in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. AcuteInfection and drug resistance · 2022
    Article
  3. Article
  4. Nutrition status andWorld journal of gastroenterology · 2018
    Review
  5. Comparison ofGastroenterology and hepatology from bed to bench · 2018
    Article
  6. Article
  7. Helicobacter pylori: Effect of coexisting diseases and update on treatment regimens.World journal of gastrointestinal pharmacology and therapeutics · 2015
    Review
  8. Article
  9. Article
  10. Article
  11. Helicobacter pylori Infection in Dialysis Patients: A Meta-Analysis.Gastroenterology research and practice · 2013
    Article
  12. Review of Helicobacter pylori infection and chronic renal failure.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2011
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Selim AydemirDepartment of Gastroenterology, Zonguldak Karaelmas University Faculty of Medicine, 67800, Zonguldak, Turkey. selimaydemir@hotmail.com
Sedat Boyacioglu
Gurden Gur
Muge Demirbilek
Fusun-Kamber Can
Murat Korkmaz
Ugur Yilmaz
Bülent Ecevit University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate susceptibility of Helicobacter pylori to amoxicillin and clarithromycin in end-stage renal disease (ESRD) patients and non-uremic controls.

methodsThe subjects with dyspeptic complaints were 33 ESRD patients and 46 age- and sex-matched non-uremic controls who exhibited H pylori on antral biopsy specimens. The two groups were age and sex matched. The H pylori strains' pattern of susceptibility to amoxicillin and clarithromycin was investigated with the agar dilution technique.

resultsNone of the H pylori strains from either group showed resistance to amoxicillin with the agar dilution method. Twelve (36.4%) of the ESRD group strains and 7 (15.2%) of the control group strains showed resistance to clarithromycin, and this difference was statistically significant (P<0.05).

conclusionResistance to amoxicillin does not appear to be an important problem in H pylori-infected ESRD and non-uremic patients in our region. In contrast, the rates of resistance to clarithromycin are high, particularly in the ESRD population.

Indexed as

AdultAmoxicillinAmpicillin ResistanceAnti-Bacterial AgentsBiopsyClarithromycinDrug Therapy, CombinationFemaleHelicobacter InfectionsHelicobacter pyloriHumansKidney Failure, ChronicMaleMiddle AgedRenal DialysisUremiaAmoxicillinAnti-Bacterial AgentsClarithromycin

Identifiers

PMID15682477
PMCPMC4250593
OpenAlexW2147734488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.