Trial reportThorax2005
Efficacy of bupropion in the indigenous Maori population in New Zealand.
Trial report in Thorax, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 7 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Korean Clinical Practice Guideline of Korean Society for Research on Nicotine and Tobacco (KSRNT) and National Evidence-based Healthcare Collaborating Agency (NECA) on Treatment of Tobacco Use 2024.Journal of Korean medical science · 2025Guideline
- Interventions for preventing weight gain after smoking cessation.The Cochrane database of systematic reviews · 2021Pooled it
- Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020Pooled it
- Effective strategies to reduce commercial tobacco use in Indigenous communities globally: A systematic review.BMC public health · 2016Pooled it
- Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2014Pooled it
- Pharmacotherapies for smoking cessation: a meta-analysis of randomized controlled trials.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2008Pooled it
- Effectiveness of smoking cessation therapies: a systematic review and meta-analysis.BMC public health · 2006Pooled it
- The Be Our Ally Beat Smoking (BOABS) study, a randomised controlled trial of an intensive smoking cessation intervention in a remote aboriginal Australian health care setting.BMC public health · 2014Trial
- Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023Review
- Modelling continuous abstinence rates over time from clinical trials of pharmacological interventions for smoking cessation.Addiction (Abingdon, England) · 2019Review
- When There Is Not Enough Evidence and When Evidence Is Not Enough: An Australian Indigenous Smoking Policy Study.Frontiers in public health · 2016Article
- An innovative team-based stop smoking competition among Māori and Pacific Island smokers: rationale and method for the study and its evaluation.BMC public health · 2013Article
- Smoking cessation in indigenous populations of Australia, New Zealand, Canada, and the United States: elements of effective interventions.International journal of environmental research and public health · 2011Review
- Using breath carbon monoxide to validate self-reported tobacco smoking in remote Australian Indigenous communities.Population health metrics · 2010Article
- Efficacy of pharmacotherapies for short-term smoking abstinance: a systematic review and meta-analysis.Harm reduction journal · 2009Article
- What potential has tobacco control for reducing health inequalities? The New Zealand situation.International journal for equity in health · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSmoking rates are high in indigenous populations and contribute to their poor health. In New Zealand the indigenous Maori population has a high rate of smoking, with around 50% of adults being smokers compared with 20% of the adult European population. A study was undertaken to determine whether bupropion is effective in the treatment of smoking cessation in the indigenous Maori population in New Zealand.
methodsA randomised, placebo controlled, double blind, parallel group study was performed in 134 Maori smokers aged 16-70 years who smoked more than 10 cigarettes per day. The main outcome measures were continued abstinence from smoking at 3 and 12 months.
resultsAt each time point continued abstinence was better for the subjects allocated to bupropion, with a risk ratio for abstinence over all time points of 2.44 (95% CI 1.22 to 4.88). The rates of continued abstinence in the bupropion and placebo groups at 3 months were 44.3% and 17.4%, respectively, with a risk ratio of 2.54 (95% CI 1.30 to 5.00). The corresponding figures at 12 months were 21.6% and 10.9%, respectively, with a risk ratio of 1.99 (95% CI 0.79 to 5.00).
conclusionBupropion is an effective treatment for smoking cessation in the indigenous Maori population in New Zealand.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.