Evidence map›Paper›PMID 15681464›Full record

ArticleJournal of virology2005

Detection and partial characterization of simian immunodeficiency virus SIVsm strains from bush meat samples from rural Sierra Leone.

Cristian Apetrei, Michael J Metzger, David Richardson, Binhua Ling, Paul T Telfer, Patricia Reed, David L Robertson, Preston A Marx

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Cristian ApetreiMicrobiology Division, Tulane National Primate Research Center, 18703 Three Rivers Rd., Covington, LA 70433, USA. capetrei@tulane.edu
Michael J Metzger
David Richardson
Binhua Ling
Paul T Telfer
Patricia Reed
David L Robertson
Preston A Marx
Tulane University · USUniversity of Manchester · GB

Funding

ZCM:A NOVEL BROAD-SPECTRUM MICROBICIDE FOR SEXUALLY TRANSMITTED INFECTIONSP51RR000164 · NCRR · TULANE UNIVERSITY OF LOUISIANA · PI MARX, PRESTON A · 1985 to 2011
$100.1M
SIV-RCM AND RELATED PRIMATE LENTIVIRUSES IN WEST AFRICAR01AI044596 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI MARX, PRESTON A · 1999 to 2003
$2.4M
NCRR NIH HHS P51 RR000164NIAID NIH HHS R01 AI044596NIAID NIH HHS R01 AI-44596
6 · The paper itself

Abstract

Human immunodeficiency virus type 2 (HIV-2) originated from simian immunodeficiency viruses (SIVs) that naturally infect sooty mangabeys (SMs; Cercocebus atys). In order to further investigate the relationship between HIV-2 and SIVsm, the SIV specific to the SM, we characterized seven new SIVsm strains from SMs sold in Sierra Leone markets as bush meat. The gag, pol, and env sequences showed that, while the viruses of all seven SMs belonged to the SIVsm-HIV-2 lineage, they were highly divergent viruses, in spite of the fact that most of the samples originated from the same geographical region. They clustered in three lineages, two of which have been previously reported. Two of the new SIVsm strains clustered differently in gag and env phylogenetic trees, suggesting SIVsm recombination that had occurred in the past. In spite of the fact that our study doubles the number of known SIVsm strains from wild SMs, none of the simian strains were close to the groups in which HIV-2 was epidemic (groups A and B).

Indexed as

AnimalsCercocebus atysDNA, ViralGenes, envGenes, gagHIV-2HumansMeatMolecular Sequence DataPhylogenySierra LeoneSimian Immunodeficiency VirusDNA, Viral

Identifiers

PMID15681464
PMCPMC546599
OpenAlexW2137418694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.