Evidence map›Paper›PMID 15676028›Full record

ReviewInternational journal of experimental pathology2005

Hepatocyte progenitors in man and in rodents--multiple pathways, multiple candidates.

Joanna Laurson, Clare Selden, Humphrey J F Hodgson

Abstract readReview
In one paragraph

Review in International journal of experimental pathology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Role of liver stem cells in hepatocarcinogenesis.World journal of stem cells · 2014
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages.Proceedings of the National Academy of Sciences of the United States of America · 2006
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joanna LaursonCentre for Hepatology, Royal Free and University College Medical School, Hampstead, London, UK.
Clare Selden
Humphrey J F Hodgson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In severe injury, liver-cell progenitors may play a role in recovery, proliferating, and subsequently differentiating into mature liver cells. Identifying these progenitors has major therapeutic potential for ex vivo pharmaceutical testing, bioartificial liver support, tissue engineering and gene therapy protocols. Potential liver-cell progenitors have been identified from bone marrow, peripheral blood, cord blood, foetal liver, adult liver and embryonic stem cells. Differences and similarities are found among cells isolated from rodents and humans. This review will discuss identifying markers and differentiation potential in in vitro and in vivo models of these putative progenitors in both humans and rodents.

Indexed as

AnimalsBone Marrow CellsCell DifferentiationFetal BloodHepatocytesHumansLiverLiver RegenerationMiceRatsStem Cells

Identifiers

PMID15676028
PMCPMC2517398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.