ArticleAntimicrobial agents and chemotherapy2005
Effects of cetylpyridinium chloride resistance and treatment on fluconazole activity versus Candida albicans.
Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Development and characterization of cetylpyridinium chloride/mucilage-based composite membranes for environmental pollution control: adsorption of Alizarin Red S and antimicrobial properties.Water science and technology : a journal of the International Association on Water Pollution Research · 2026Article
- Repurposing Mouthwashes: Antifungal and Antibiofilm Abilities of Commercially Available Mouthwashes AgainstAntibiotics (Basel, Switzerland) · 2025Article
- Sub-Therapeutic Concentrations of Hexetidine Induce Virulence Gene Expression inInfection and drug resistance · 2025Article
- Novel Keto-Alkyl-Pyridinium Antifungal Molecules Active in Models ofAntimicrobial agents and chemotherapy · 2023Article
- Novel keto-alkyl-pyridinium antifungal molecules active in models of in vivobioRxiv : the preprint server for biology · 2023Article
- Novel Colloidal Nanocarrier of Cetylpyridinium Chloride: Antifungal Activities onJournal of fungi (Basel, Switzerland) · 2020Article
- Deciphering biophysical signatures for microbiological applications.Lasers in medical science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Mouthwash antiseptic cetylpyridinium chloride (CPC) has potent activity against Candida albicans; however, two of five azole-resistant strains showed reduced CPC susceptibility. To further examine the potential for cross-resistance, CPC-resistant mutants were selected in vitro and their fluconazole susceptibility was tested. MICs were unchanged, and trailing growth generally decreased. With CPC-fluconazole combinations, both antagonism and synergism were observed, which can be explained, in part, by CDR1-CDR2 multidrug transporter upregulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.