ArticleAntimicrobial agents and chemotherapy2005
Interspecies recombination in type II topoisomerase genes is not a major cause of fluoroquinolone resistance in invasive Streptococcus pneumoniae isolates in the United States.
Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Antimicrobial Resistance in Oral Healthcare: A Growing Concern in Dentistry.Dentistry journal · 2025Review
- Convergent impact of vaccination and antibiotic pressures on pneumococcal populations.Cell chemical biology · 2024Review
- Deciphering the distance to antibiotic resistance for the pneumococcus using genome sequencing data.Scientific reports · 2017Article
- Biological and Epidemiological Features of Antibiotic-Resistant Streptococcus pneumoniae in Pre- and Post-Conjugate Vaccine Eras: a United States Perspective.Clinical microbiology reviews · 2016Review
- Resistance surveillance studies: a multifaceted problem--the fluoroquinolone example.Infection · 2012Review
- Molecular characterization of emerging non-levofloxacin-susceptible pneumococci isolated from children in South Africa.Journal of clinical microbiology · 2009Article
- Fluoroquinolone resistance in atypical pneumococci and oral streptococci: evidence of horizontal gene transfer of fluoroquinolone resistance determinants from Streptococcus pneumoniae.Antimicrobial agents and chemotherapy · 2007Article
- Fitness costs of fluoroquinolone resistance in Streptococcus pneumoniae.Antimicrobial agents and chemotherapy · 2007Article
- First characterization of fluoroquinolone resistance in Streptococcus suis.Antimicrobial agents and chemotherapy · 2007Article
- Fluoroquinolone resistance in invasive Streptococcus pyogenes isolates due to spontaneous mutation and horizontal gene transfer.Antimicrobial agents and chemotherapy · 2006Article
- Molecular evolution perspectives on intraspecific lateral DNA transfer of topoisomerase and gyrase loci in Streptococcus pneumoniae, with implications for fluoroquinolone resistance development and spread.Antimicrobial agents and chemotherapy · 2005Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mutations in the topoisomerase type II enzymes account for fluoroquinolone resistance in Streptococcus pneumoniae. These mutations can arise spontaneously or be transferred by intraspecies or interspecies recombination, primarily with viridans streptococci. We analyzed the nucleotide sequences of the quinolone resistance-determining regions of 49 invasive levofloxacin-resistant pneumococcal isolates and did not find any evidence for interspecies recombination.
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