Evidence map›Paper›PMID 15673763›Full record

ArticleAntimicrobial agents and chemotherapy2005

Antistaphylococcal activity of dalbavancin, an experimental glycopeptide.

Gengrong Lin, Kim Credito, Lois M Ednie, Peter C Appelbaum

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Newer glycopeptide antibiotics for treatment of complicated skin and soft tissue infections: systematic review, network meta-analysis and cost analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2018
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Antibiotics and bacterial resistance in the 21st century.Perspectives in medicinal chemistry · 2014
    Review
  13. Article
  14. Newer antibacterial drugs for a new century.Expert opinion on investigational drugs · 2010
    Review
  15. Review
  16. Article
  17. Article
  18. Dalbavancin (zeven), a novel glycopeptide for resistant gram-positive organisms.P & T : a peer-reviewed journal for formulary management · 2008
    Article
  19. Dalbavancin.Drugs · 2008
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gengrong LinDepartment of Pathology, Hershey Medical Center, P.O. Box 850, Hershey, PA 17033, USA.
Kim Credito
Lois M Ednie
Peter C Appelbaum
Hershey (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dalbavancin, tested against 146 staphylococci, was more potent than other drugs tested, with an MIC at which 50% of staphylococci were inhibited of 0.03 microg/ml and an MIC at which 90% of staphylococci were inhibited of 0.06 microg/ml by microdilution. For all strains, MICs of vancomycin, linezolid, ranbezolid, oritavancin, daptomycin, and quinupristin-dalfopristin were </=4.0 microg/ml. Dalbavancin was bactericidal at four times the MIC against all six strains tested.

Indexed as

Anti-Bacterial AgentsColony Count, MicrobialDrug Resistance, BacterialGlycopeptidesKineticsMethicillin ResistanceMicrobial Sensitivity TestsStaphylococcusTeicoplaninVancomycin ResistanceAnti-Bacterial AgentsdalbavancinGlycopeptidesTeicoplanin

Identifiers

PMID15673763
PMCPMC547276
OpenAlexW2137640066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.