ArticleAntimicrobial agents and chemotherapy2005
Prevalence and subtypes of ciprofloxacin-resistant Campylobacter spp. in commercial poultry flocks before, during, and after treatment with fluoroquinolones.
Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- A systematic review and meta-analysis of Penner serotype prevalence of Campylobacter jejuni in low- and middle-income countries.PloS one · 2021Pooled it
- Longitudinal study of prevalence and antimicrobial resistance of thermotolerantMicrobiology spectrum · 2026Article
- Immunoglobulin Y-Based Lateral Flow Immunoassay Strip Test for Detecting Ciprofloxacin Antibiotic in Raw Pork Samples.Foods (Basel, Switzerland) · 2025Article
- Antimicrobial resistance: Past, present, and way forward.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2024Article
- Growth kinetics and fitness of fluoroquinolone resistant and susceptibleFrontiers in veterinary science · 2023Article
- Influence of Single Dose Enrofloxacin Injection on Development of Fluoroquinolone Resistance inAntibiotics (Basel, Switzerland) · 2022Article
- Emerging patterns of fluoroquinolone resistance inMicrobial genomics · 2022Article
- Effect of Danofloxacin Treatment on the Development of Fluoroquinolone Resistance inAntibiotics (Basel, Switzerland) · 2022Article
- Whole Resistome Analysis inFrontiers in microbiology · 2021Article
- Prevalence ofFrontiers in microbiology · 2021Article
- Article
- Trends in fluoroquinolone resistance in Campylobacter.Microbial genomics · 2018Article
- Antibiotic resistance: a rundown of a global crisis.Infection and drug resistance · 2018Review
- Exploiting Bacterial Whole-Genome Sequencing Data for Evaluation of Diagnostic Assays: Campylobacter Species Identification as a Case Study.Journal of clinical microbiology · 2016Article
- Nonmedical Uses of Antibiotics: Time to Restrict Their Use?PLoS biology · 2015Article
- Antibiotics in agriculture and the risk to human health: how worried should we be?Evolutionary applications · 2015Review
- MLST genotypes and antibiotic resistance of Campylobacter spp. isolated from poultry in Grenada.BioMed research international · 2013Article
- Do antibiotic residues in soils play a role in amplification and transmission of antibiotic resistant bacteria in cattle populations?Frontiers in microbiology · 2013Article
- Antimicrobial resistance mechanisms among Campylobacter.BioMed research international · 2013Review
- Evolution of an agriculture-associated disease causing Campylobacter coli clade: evidence from national surveillance data in Scotland.PloS one · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Five commercial broiler chicken flocks were treated with either difloxacin or enrofloxacin for a clinically relevant infection, as instructed by a veterinarian. Campylobacters were isolated from individual fecal samples and from samples associated with the broiler environment before, during, and after treatment. Ciprofloxacin-resistant Campylobacter jejuni and/or C. coli strains were detected pretreatment in four flocks, but they constituted a very small proportion of the campylobacters present. When the broilers were treated with a fluoroquinolone, a rapid increase in the proportion of ciprofloxacin-resistant campylobacters was observed. During treatment nearly 100% of campylobacters were resistant, and in some flocks a high proportion of resistant strains persisted for up to 4 weeks after treatment. Prior to treatment a variety of campylobacter subtypes were present. During and after treatment considerable changes in both species and subtype prevalence were observed, but no single fluoroquinolone-resistant clone became dominant. Instead, resistant C. coli strains or a mixture of resistant C. coli and C. jejuni strains became dominant, whereas susceptible C. jejuni strains had usually been dominant prior to treatment. The resistant subtypes which emerged and became dominant were not always the same as those detected pretreatment. The persistence of resistant strains for up to 4 weeks posttreatment has important implications for any strategy designed to avoid the introduction of such strains into the food chain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.