Trial reportAnnals of family medicine
Cost-effectiveness of enhancing primary care depression management on an ongoing basis.
Trial report in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Diagnostic accuracy of traditional and deep learning methods for detecting depression based on speech features: a systematic review and meta-analysis.BMC psychiatry · 2025Pooled it
- Cost-effectiveness of collaborative care for the treatment of depressive disorders in primary care: a systematic review.PloS one · 2015Pooled it
- The estimation of utility weights in cost-utility analysis for mental disorders: a systematic review.PharmacoEconomics · 2013Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- Does GP training in depression care affect patient outcome? - A systematic review and meta-analysis.BMC health services research · 2012Pooled it
- Do productivity costs matter?: the impact of including productivity costs on the incremental costs of interventions targeted at depressive disorders.PharmacoEconomics · 2011Pooled it
- Cost-effectiveness of collaborative care for the treatment of major depressive disorder in primary care. A systematic review.BMC health services research · 2010Pooled it
- Quantity and Quality of Economic Evaluations in U.S. Nursing Research, 1997-2015: A Systematic Review.Nursing researchPooled it
- Cost-effectiveness of a community-integrated home-based depression intervention in older African Americans.Journal of the American Geriatrics Society · 2014Trial
- Intervention impact on depression product appraisal and purchasing behavior by employers: a randomized trial.BMC health services research · 2014Trial
- Yield of practice-based depression screening in VA primary care settings.Journal of general internal medicine · 2012Trial
- Prognostic factors, course, and outcome of depression among older primary care patients: the PROSPECT study.Aging & mental health · 2012Trial
- Stakeholder benefit from depression disease management: differences by rurality?The journal of behavioral health services & research · 2011Trial
- The association of depression and pain with health-related quality of life, disability, and health care use in cancer patients.Journal of pain and symptom management · 2010Trial
- Advantages of using estimated depression-free days for evaluating treatment efficacy.Psychiatric services (Washington, D.C.) · 2010Trial
- Generalist care managers for the treatment of depressed medicaid patients in North Carolina: a pilot study.BMC family practice · 2007Trial
- Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial.BMC health services research · 2007Trial
- RCT of a care manager intervention for major depression in primary care: 2-year costs for patients with physical vs psychological complaints.Annals of family medicineTrial
- Cost effectiveness of telecare management for pain and depression in patients with cancer: results from a randomized trial.General hospital psychiatryTrial
- The Indiana Cancer Pain and Depression (INCPAD) trial Design of a telecare management intervention for cancer-related symptoms and baseline characteristics of study participants.General hospital psychiatryTrial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeAlthough potentially costly, enhancing primary care depression management on an ongoing basis results in substantial long-term treatment effectiveness. The purpose of this article is to compare the cost-effectiveness of this approach with that of usual care.
methodsThe study was conducted in 12 community primary care practices randomized to enhanced or usual care after stratification by baseline practice patterns. Practices assigned to enhanced care encouraged depressed patients to engage in active treatment, using practice nurses to provide regularly scheduled care management during the course of 24 months. We analyze outcomes for 211 adults (73.4% of potential eligible patients) beginning a new treatment episode for major depression determined by previsit screening. Outcomes included blinded estimates of days free of depression impairment as well as health care costs for 2 years.
resultsEnhanced care significantly increased the number of days free of depression impairment for 2 years when compared with usual care (647.6 days vs 588.2 days, P <.01). The incremental cost-effectiveness ratio for enhanced care ranged from 9,592 dollars to 14,306 dollars per quality-adjusted life-year (QALY). The number of incremental days free of depression impairment increased between the first year and the second year (23.0 vs 36.4, respectively, P <.001) while incremental health plan costs decreased significantly (568 dollars vs -12 dollars, P <.001).
conclusionsEnhancing primary care depression management on an ongoing basis should be considered for adoption by policy and health plan leaders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.