Evidence map›Paper›PMID 15664972›Full record

ArticleInfection and immunity2005

Plasmodium falciparum merozoite surface protein 6 displays multiple targets for naturally occurring antibodies that mediate monocyte-dependent parasite killing.

Subhash Singh, Soe Soe, Christian Roussilhon, Giampietro Corradin, Pierre Druilhe

Abstract read
In one paragraph

Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Subhash SinghBio-medical Parasitology Unit, Institute Pasteur, 28 rue du Dr Roux, 75015 Paris, France.
Soe Soe
Christian Roussilhon
Giampietro Corradin
Pierre Druilhe

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmodium falciparum MSP6 is a merozoite surface antigen that shows organization and sequence homologies similar to those of MSP3. Within its C-terminus conserved region, it presents some epitopes that are cross-reactive with MSP3 and others that are not, both being targets of naturally occurring antibodies that block the P. falciparum erythrocytic cycle in cooperation with monocytes.

Indexed as

Amino Acid SequenceAnimalsAntibodiesAntigens, ProtozoanEpitopesHumansMalaria, FalciparumMembrane ProteinsMolecular Sequence DataMonocytesPlasmodium falciparumProtozoan ProteinsAntibodiesAntigens, ProtozoanEpitopesMembrane Proteinsmerozoite surface protein 3, Plasmodiummerozoite surface protein 6, PlasmodiumProtozoan Proteins

Identifiers

PMID15664972
PMCPMC547023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.