Evidence map›Paper›PMID 15663861›Full record

ArticleEmerging infectious diseases2004

SARS molecular detection external quality assurance.

Christian Drosten, Hans Wilhelm Doerr, Wilina Lim, Klaus Stöhr, Matthias Niedrig

Abstract readMulticenter Study
In one paragraph

Article in Emerging infectious diseases, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. International external quality assessment for SARS-CoV-2 molecular detection and survey on clinical laboratory preparedness during the COVID-19 pandemic, April/May 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Article
  2. Article
  3. Assay optimization for molecular detection of Zika virus.Bulletin of the World Health Organization · 2016
    Article
  4. Article
  5. Performance and clinical validation of the RealStar MERS-CoV Kit for detection of Middle East respiratory syndrome coronavirus RNA.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2014
    Article
  6. Article
  7. Review
  8. Singleplex real-time RT-PCR for detection of influenza A virus and simultaneous differentiation of A/H1N1v and evaluation of the RealStar influenza kit.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2011
    Article
  9. Article
  10. Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian DrostenBernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Hans Wilhelm Doerr
Wilina Lim
Klaus Stöhr
Matthias Niedrig

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inactivated severe acute respiratory syndrome-associated coronavirus samples were used for an external quality assurance study within the World Health Organization SARS Reference and Verification Network and other reference institutions. Of 58 participants, 51 correctly detected virus in all samples > or =9,400 RNA copies per milliliter and none in negative samples. Commercial test kits significantly improved the outcome.

Indexed as

HumansLaboratoriesQuality ControlReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionRNA, ViralSevere acute respiratory syndrome-related coronavirusRNA, Viral

Identifiers

PMID15663861
PMCPMC3323363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.