ReviewCurrent opinion in cell biology2005
Kinetochore-spindle microtubule interactions during mitosis.
Review in Current opinion in cell biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 99 citations in OpenAlex.
- Cellular senescence-related gene signature as a valuable predictor of prognosis in hepatocellular carcinoma.Aging · 2023Article
- SPC25 promotes proliferation and stemness of hepatocellular carcinoma cells via the DNA-PK/AKT/Notch1 signaling pathway.International journal of biological sciences · 2022Article
- Shugosin 2 is a biomarker for pathological grading and survival prediction in patients with gliomas.Scientific reports · 2021Article
- Article
- Antagonism between the dynein and Ndc80 complexes at kinetochores controls the stability of kinetochore-microtubule attachments during mitosis.The Journal of biological chemistry · 2018Article
- Identification of conserved genes triggering puberty in European sea bass males (Dicentrarchus labrax) by microarray expression profiling.BMC genomics · 2017Article
- Pellino 1 inactivates mitotic spindle checkpoint by targeting BubR1 for ubiquitinational degradation.Oncotarget · 2017Article
- All that is old does not wither: Conservation of outer kinetochore proteins across all eukaryotes?The Journal of cell biology · 2017Article
- Shape Transformation of the Nuclear Envelope during Closed Mitosis.Biophysical journal · 2016Article
- NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity.Scientific reports · 2016Article
- Compartmentalized Toxoplasma EB1 bundles spindle microtubules to secure accurate chromosome segregation.Molecular biology of the cell · 2015Article
- Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas.Oncotarget · 2015Article
- Hec1 inhibition alters spindle morphology and chromosome alignment in porcine oocytes.Molecular biology reports · 2014Article
- Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.Cell cycle (Georgetown, Tex.) · 2014Article
- Article
- Comprehensive analysis of LANA interacting proteins essential for viral genome tethering and persistence.PloS one · 2013Article
- Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore.Nature reviews. Molecular cell biology · 2013Review
- The Ndc80 kinetochore complex directly modulates microtubule dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Coiled-coil networking shapes cell molecular machinery.Molecular biology of the cell · 2012Article
- Xenopus Shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complex.The EMBO journal · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The kinetochore is a proteinaceous structure that assembles onto centromeric DNA and mediates chromosome attachment to microtubules during mitosis. This description is deceivingly simple: recent proteomic studies suggest that the diminutive kinetochores of Saccharomyces cerevisiae are comprised of at least 60 proteins organized into as many as 14 different subcomplexes. Many of these proteins, such as the centromeric histone variant CENP-A, and entire subcomplexes, such as the Ndc80(Hec1) complex, are conserved from yeast to humans despite the diverse nature of the DNA sequences on which they assemble. There have recently been advances in our understanding of the molecular basis of how kinetochores establish dynamic attachments to spindle microtubules, and how these attachments are correctly oriented to ensure segregation of sister chromatids to daughter cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.