ArticlePLoS biology2005
Major structural differences and novel potential virulence mechanisms from the genomes of multiple campylobacter species.
Article in PLoS biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 265 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
265 citing papers in PubMed, 547 citations in OpenAlex.
- Impact of Encapsulated Iron Availability on the Growth Kinetics ofPathogens (Basel, Switzerland) · 2026Article
- Transport of the abundant intestinal amino acid glutamine by the enteric pathogenMicrobiology (Reading, England) · 2026Article
- The Global Challenge ofTropical medicine and infectious disease · 2025Review
- Article
- Glycoengineering with neuraminic acid analogs to label lipooligosaccharides and detect native sialyltransferase activity in gram-negative bacteria.Glycobiology · 2024Article
- Clinical manifestations, antimicrobial resistance and genomic feature analysis of multidrug-resistant Elizabethkingia strains.Annals of clinical microbiology and antimicrobials · 2024Article
- Genomic Analysis Points to Multiple Genetic Mechanisms for Non-TransformableMicroorganisms · 2024Article
- The zoonotic pathogen Wohlfahrtiimonas chitiniclastica - current findings from a clinical and genomic perspective.BMC microbiology · 2024Review
- Molecular Targets inBiomolecules · 2023Review
- Comparative genomic analysis ofFrontiers in microbiology · 2023Article
- Genomic insights into phage-host interaction in the deep-sea chemolithoautotrophic Campylobacterota, Nitratiruptor.ISME communications · 2022Article
- Roles of Aerotolerance, Biofilm Formation, and Viable but Non-Culturable State in the Survival ofMicroorganisms · 2022Review
- Review
- Pan-Genome Analysis of Campylobacter: Insights on the Genomic Diversity and Virulence Profile.Microbiology spectrum · 2022Article
- Cryptic Prophages Contribution forMicroorganisms · 2022Article
- Transient internalization ofMicrobiology (Reading, England) · 2022Article
- Biomolecule sulphation and novel methylations related to Guillain-Barré syndrome-associatedMicrobial genomics · 2021Article
- AMicrobial genomics · 2021Article
- Cytolethal distending toxin: from genotoxin to a potential biomarker and anti-tumor target.World journal of microbiology & biotechnology · 2021Review
- Bioinformatic Analysis of theFrontiers in microbiology · 2021Article
205 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sequencing and comparative genome analysis of four strains of Campylobacter including C. lari RM2100, C. upsaliensis RM3195, and C. coli RM2228 has revealed major structural differences that are associated with the insertion of phage- and plasmid-like genomic islands, as well as major variations in the lipooligosaccharide complex. Poly G tracts are longer, are greater in number, and show greater variability in C. upsaliensis than in the other species. Many genes involved in host colonization, including racR/S, cadF, cdt, ciaB, and flagellin genes, are conserved across the species, but variations that appear to be species specific are evident for a lipooligosaccharide locus, a capsular (extracellular) polysaccharide locus, and a novel Campylobacter putative licABCD virulence locus. The strains also vary in their metabolic profiles, as well as their resistance profiles to a range of antibiotics. It is evident that the newly identified hypothetical and conserved hypothetical proteins, as well as uncharacterized two-component regulatory systems and membrane proteins, may hold additional significant information on the major differences in virulence among the species, as well as the specificity of the strains for particular hosts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.