Evidence map›Paper›PMID 15660122›Full record

ReviewJournal of human hypertension2005

Current status of angiotensin receptor blockers for the treatment of cardiovascular diseases: focus on telmisartan.

S G Chrysant, G S Chrysant, A Desai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of human hypertension, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. The pleiotropic effects of angiotensin receptor blockers.Journal of clinical hypertension (Greenwich, Conn.) · 2006
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

S G ChrysantUniversity of Oklahoma, Oklahoma Cardiovascular and Hypertension Center, Oklahoma City, OK 73132-4904, USA. schrysant@yahoo.com
G S Chrysant
A Desai

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poorly controlled hypertension is a major risk for cardiovascular morbidity and mortality, strokes, heart failure and renal failure. Despite these devastating complications, blood pressure control of </=140/90 mmHg, which is above the current standard, is very poor worldwide, accounting for 34% of hypertensive patients in the United States, and 6% in other countries. The reasons for this poor control of blood pressure include lack of aggressive treatment by physicians, especially for the systolic blood pressure, drug selection and patient compliance. The blood pressure follows a circadian rhythm and is the highest between 0600 to 1200 h, when most complications occur. Long-acting drugs that extend their action to cover this vulnerable period are preferable, especially those that block the renin-angiotensin-aldosterone system, such as ACE inhibitors and angiotensin receptor blockers, and are the most effective in controlling blood pressure and preventing or reducing its cardiovascular and renal complications. With respect to the angiotensin receptor blockers, telmisartan has been demonstrated by several studies to be the longest acting among its class of drugs and to effectively prevent the early morning rise of blood pressure.

Indexed as

Angiotensin II Type 1 Receptor BlockersBenzimidazolesBenzoatesBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmHeart FailureHumansHypertensionRenal InsufficiencyStrokeTelmisartanTreatment OutcomeAngiotensin II Type 1 Receptor BlockersBenzimidazolesBenzoatesTelmisartan

Identifiers

PMID15660122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.