ArticleMolecular biology of the cell2005
Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex.
Article in Molecular biology of the cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 61 citations in OpenAlex.
- Article
- Article
- IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport.Cellular and molecular life sciences : CMLS · 2024Article
- Essential requirement for IER3IP1 in B cell development.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- IER3IP1 is critical for maintaining glucose homeostasis through regulating the endoplasmic reticulum function and survival of β cells.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Exploring the eukaryotic Yip and REEP/Yop superfamily of membrane-shaping adapter proteins (MSAPs): A cacophony or harmony of structure and function?Frontiers in molecular biosciences · 2022Review
- Computed structures of core eukaryotic protein complexes.Science (New York, N.Y.) · 2021Article
- APeerJ · 2021Article
- Article
- Expression characterization and transcription regulation analysis of porcine Yip1 domain family member 3 gene.Asian-Australasian journal of animal sciences · 2020Article
- YIPF2 is a novel Rab-GDF that enhances HCC malignant phenotypes by facilitating CD147 endocytic recycle.Cell death & disease · 2019Article
- A guanine nucleotide exchange factor (GEF) limits Rab GTPase-driven membrane fusion.The Journal of biological chemistry · 2018Article
- GOLGI TRANSPORT 1B Regulates Protein Export from the Endoplasmic Reticulum in Rice Endosperm Cells.The Plant cell · 2016Article
- Overexpression of Sly41 suppresses COPII vesicle-tethering deficiencies by elevating intracellular calcium levels.Molecular biology of the cell · 2016Article
- Article
- The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites.The EMBO journal · 2013Article
- Post-translational regulation of sucrose transporters by direct protein-protein interactions.Frontiers in plant science · 2013Article
- Identification of discrete sites in Yip1A necessary for regulation of endoplasmic reticulum structure.PloS one · 2013Article
- Linking membrane trafficking and intestinal homeostasis.Tissue barriers · 2013Article
- A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum.Cell death and differentiation · 2012Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Yeast Yip1p is a member of a conserved family of transmembrane proteins that interact with Rab GTPases. Previous studies also have indicated a role for Yip1p in the biogenesis of endoplasmic reticulum (ER)-derived COPII transport vesicles. In this report, we describe the identification and characterization of the uncharacterized open reading frame YER074W-A as a novel multicopy suppressor of the thermosensitive yip1-4 strain. We have termed this gene Yip One Suppressor 1 (YOS1). Yos1p is essential for growth and for function of the secretory pathway; depletion or inactivation of Yos1p blocks transport between the ER and the Golgi complex. YOS1 encodes an integral membrane protein of 87 amino acids that is conserved in eukaryotes. Yos1p localizes to ER and Golgi membranes and is efficiently packaged into ER-derived COPII transport vesicles. Yos1p associates with Yip1p and Yif1p, indicating Yos1p is a novel subunit of the Yip1p-Yif1p complex.
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Registered trials
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