ArticleProceedings of the National Academy of Sciences of the United States of America2005
Role of SDF1 chemokine in the development of lateral line efferent and facial motor neurons.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- Mechanical interactions dynamically influence rosette morphogenesis in the migrating zebrafish posterior lateral line primordium.Development (Cambridge, England) · 2026Article
- The influence of SDF-1 (CXCL12) gene in health and disease: a review of literature.Biophysical reviews · 2025Review
- Article
- Development and migration of the zebrafish rhombencephalic octavolateral efferent neurons.The Journal of comparative neurology · 2021Article
- Talking back: Development of the olivocochlear efferent system.Wiley interdisciplinary reviews. Developmental biology · 2018Review
- Cxcl12a inducesDevelopment (Cambridge, England) · 2018Article
- A framework for understanding morphogenesis and migration of the zebrafish posterior Lateral Line primordium.Mechanisms of development · 2017Review
- Cadherin-2 Is Required Cell Autonomously for Collective Migration of Facial Branchiomotor Neurons.PloS one · 2016Article
- Chemokine-guided cell migration and motility in zebrafish development.The EMBO journal · 2015Review
- Facial motor neuron migration advances.Current opinion in neurobiology · 2013Review
- Collective cell migration of epithelial and mesenchymal cells.Cellular and molecular life sciences : CMLS · 2013Review
- Perturbation of invadolysin disrupts cell migration in zebrafish (Danio rerio).Experimental cell research · 2013Article
- CXCL12 signaling in the development of the nervous system.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2012Review
- Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair.Trends in neurosciences · 2012Review
- olig2-Expressing hindbrain cells are required for migrating facial motor neurons.Developmental dynamics : an official publication of the American Association of Anatomists · 2012Article
- Article
- Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity.Development (Cambridge, England) · 2011Article
- Prickle1b mediates interpretation of migratory cues during zebrafish facial branchiomotor neuron migration.Developmental dynamics : an official publication of the American Association of Anatomists · 2010Article
- Afferent neurons of the zebrafish lateral line are strict selectors of hair-cell orientation.PloS one · 2009Article
- Specificity of afferent synapses onto plane-polarized hair cells in the posterior lateral line of the zebrafish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most sensory systems are innervated by efferent neurons as well as by afferent neurons. The efferent innervation modulates the sensitivity of the receptor cells or of the sensory terminals. In the posterior lateral line system of the zebrafish, two efferent nuclei have been described in the hindbrain. Here we examine the development of the efferent neurons. We show that their axons are guided toward the target organ along the lateral line nerve while their cell bodies migrate posteriorward across rhombomeres to achieve their final position in rhombomeres 6/7. This migration depends on the SDF1 chemokine. We show that the migration of motor neurons of the facial nucleus from rhombomere 4 to 6 is also affected in sdf1a morphants (embryos injected with morpholine-conjugated antisense oligonucleotides). We propose that SDF1/CXCR4-mediated cell migration is preferentially associated with movement along the anteroposterior axis of the animal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.