ReviewMolecular neurobiology2004
Gap junctions: their importance for the dynamics of neural circuits.
Review in Molecular neurobiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Frequency-dependent coupling in response to oscillatory inputs in minimal networks of electrically coupled nodes: Gap junction networks and spatially extended neurons.Biological cybernetics · 2026Article
- D-type K+ current rules the function of electrically coupled neurons in a species-specific fashion.The Journal of general physiology · 2023Article
- Function and Plasticity of Electrical Synapses in the Mammalian Brain: Role of Non-Junctional Mechanisms.Biology · 2022Review
- Characteristics of Kundalini-Related Sensory, Motor, and Affective Experiences During Tantric Yoga Meditation.Frontiers in psychology · 2022Article
- Extensive GJD2 Expression in the Song Motor Pathway Reveals the Extent of Electrical Synapses in the Songbird Brain.Biology · 2021Article
- Gap junctions and expression of Cx36, Cx43 and Cx45 in the posterodorsal medial amygdala of adult rats.Histology and histopathology · 2020Article
- Beyond plasticity: the dynamic impact of electrical synapses on neural circuits.Nature reviews. Neuroscience · 2019Review
- Dynamic intercellular transport modulates the spatial patterning of differentiation during early neural commitment.Nature communications · 2018Article
- Article
- Bioelectric signaling in regeneration: Mechanisms of ionic controls of growth and form.Developmental biology · 2018Review
- Electrical Synapses Enhance and Accelerate Interneuron Recruitment in Response to Coincident and Sequential Excitation.Frontiers in cellular neuroscience · 2018Article
- Gap junctional signaling in pattern regulation: Physiological network connectivity instructs growth and form.Developmental neurobiology · 2017Review
- Gap Junction-Mediated Signaling from Motor Neurons Regulates Motor Generation in the Central Circuits of LarvalThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- GAP junctional communication in brain secondary organizers.Development, growth & differentiation · 2016Review
- Molecular layer interneurons of the cerebellum: developmental and morphological aspects.Cerebellum (London, England) · 2015Review
- Optogenetic mapping of cerebellar inhibitory circuitry reveals spatially biased coordination of interneurons via electrical synapses.Cell reports · 2014Article
- Rectifying electrical synapses can affect the influence of synaptic modulation on output pattern robustness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Gap junction expression is required for normal chemical synapse formation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Using a model to assess the role of the spatiotemporal pattern of inhibitory input and intrasegmental electrical coupling in the intersegmental and side-to-side coordination of motor neurons by the leech heartbeat central pattern generator.Journal of neurophysiology · 2008Article
- Genes and (common) pathways underlying drug addiction.PLoS computational biology · 2008Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrical coupling through gap junctions constitutes a mode of signal transmission between neurons (electrical synaptic transmission). Originally discovered in invertebrates and in lower vertebrates, electrical synapses have recently been reported in immature and adult mammalian nervous systems. This has renewed the interest in understanding the role of electrical synapses in neural circuit function and signal processing. The present review focuses on the role of gap junctions in shaping the dynamics of neural networks by forming electrical synapses between neurons. Electrical synapses have been shown to be important elements in coincidence detection mechanisms and they can produce complex input-output functions when arranged in combination with chemical synapses. We postulate that these synapses may also be important in redefining neuronal compartments, associating anatomically distinct cellular structures into functional units. The original view of electrical synapses as static connecting elements in neural circuits has been revised and a considerable amount of evidence suggests that electrical synapses substantially affect the dynamics of neural circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.