Evidence map›Paper›PMID 15653821›Full record

ReviewClinical microbiology reviews2005

Surface proteins of Streptococcus agalactiae and related proteins in other bacterial pathogens.

Gunnar Lindahl, Margaretha Stålhammar-Carlemalm, Thomas Areschoug

Open access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 347 citations in OpenAlex.

  1. Trial
  2. Antibacterial Activity of Rosmarinic Acid AgainstAnimals : an open access journal from MDPI · 2026
    Article
  3. Review
  4. Zoonotic Approach toInternational journal of microbiology · 2026
    Article
  5. Article
  6. Article
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  10. Article
  11. Article
  12. Review
  13. Article
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  15. Article
  16. Antimicrobial Resistance and Virulence Genes ofJournal of veterinary research · 2022
    Article
  17. Article
  18. The long and the short of Periscope Proteins.Biochemical Society transactions · 2022
    Review
  19. Alterations in GenesPathogens (Basel, Switzerland) · 2022
    Article
  20. Nitric Oxide Production and Effects in Group BPathogens (Basel, Switzerland) · 2022
    Article

103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gunnar LindahlDepartment of Medical Microbiology, Dermatology and Infection, Lund University, Sölvegatan 23, SE-22362 Lund, Sweden. gunnar.lindahl@mmb.lu.se
Margaretha Stålhammar-Carlemalm
Thomas Areschoug
Lund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptococcus agalactiae (group B Streptococcus) is the major cause of invasive bacterial disease, including meningitis, in the neonatal period. Although prophylactic measures have contributed to a substantial reduction in the number of infections, development of a vaccine remains an important goal. While much work in this field has focused on the S. agalactiae polysaccharide capsule, which is an important virulence factor that elicits protective immunity, surface proteins have received increasing attention as potential virulence factors and vaccine components. Here, we summarize current knowledge about S. agalactiae surface proteins, with emphasis on proteins that have been characterized immunochemically and/or elicit protective immunity in animal models. These surface proteins have been implicated in interactions with human epithelial cells, binding to extracellular matrix components, and/or evasion of host immunity. Of note, several S. agalactiae surface proteins are related to surface proteins identified in other bacterial pathogens, emphasizing the general interest of the S. agalactiae proteins. Because some S. agalactiae surface proteins elicit protective immunity, they hold promise as components in a vaccine based only on proteins or as carriers in polysaccharide conjugate vaccines.

Indexed as

Bacterial ProteinsMembrane ProteinsAmino Acid SequenceAnimalsAntigens, BacterialBacteriaCattleFemaleGene Expression Regulation, BacterialHumansInfant, NewbornMiceMolecular Sequence DataRatsStreptococcal InfectionsStreptococcus agalactiaeAntigens, BacterialBacterial ProteinsMembrane ProteinsRib protein, Streptococcus agalactiae

Identifiers

PMID15653821
PMCPMC544178
OpenAlexW2123958668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.