Evidence map›Paper›PMID 15652604›Full record

ArticleLancet (London, England)

Global burden of hypertension: analysis of worldwide data.

Patricia M Kearney, Megan Whelton, Kristi Reynolds, Paul Muntner, Paul K Whelton, Jiang He

11 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Lancet (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 11 registered trials, which are not on this map. Cited by 3,017 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3,017citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00046566 nacompletednot on this map

Clinical Trial of Dietary Protein on Blood Pressure

TypeinterventionalSponsorTulane UniversityRan2002 to 2008Enrolled352ConditionsCardiovascular Diseases, Hypertension, Heart DiseasesArmsSoy protein-milk protein-carbohydrate, Milk protein-carbohydrate-soy protein, Carbohydrate-soy protein-milk protein
NCT00107744 nacompletednot on this map

Clinical Trial of Protein and Blood Pressure

TypeinterventionalSponsorTulane UniversityRan2003 to 2008Enrolled352ConditionsHypertension, HypercholesterolemiaArmsSoy protein-milk protein-carbohydrate, Milk protein-carbohydrate-soy protein, Carbohydrate-soy protein-milk protein
NCT01628172 nacompletednot on this map

Renal Sympathetic Denervation for the Management of Chronic Hypertension

TypeinterventionalSponsorVivek ReddyRan2011 to 2014Enrolled96ConditionsUncontrolled HypertensionArmsBiosense Webster Celcius Thermacool catheter
NCT01628198 naterminatednot on this map

Impact of Renal SympAthetic DenerVation on Chronic HypErtension

TypeinterventionalSponsorVivek ReddyRan2011 to 2015Enrolled38ConditionsUncontrolled HypertensionArmsCelcius Thermacool Catheter or Chilli II Cooled Ablation Catheter
NCT02380157 phase4completednot on this map

Oral Potassium Supplementation in Healthy Men - Interactions With the Renin-angiotensin-aldosterone System and the Sympathetic Nervous System

TypeinterventionalSponsorGlostrup University Hospital, CopenhagenRan2015 to 2016Enrolled25ConditionsBlood Pressure, HypertensionArmsKaleorid, 750mg (trade name), Potassium chloride (active substance), Placebo
NCT03368417 naterminatednot on this map

A Randomised Controlled Trial to Improve Hypertension Outcomes Using Wireless Home Blood Pressure Monitoring With Automatic Outcome-based Feedback and Financial Incentives

TypeinterventionalSponsorDuke-NUS Graduate Medical SchoolRan2017 to 2019Enrolled42ConditionsHypertensionArmsUsual Care, Wireless HBPM System, BP Monitoring Incentives
NCT03588520 naunknown statusnot on this map

Investigation Of The Utility Of Home Blood Pressure Measurements Towards Improving The Management Of Hypertension In Patients In Stage 3 And 4 Chronic Kidney Disease

TypeinterventionalSponsorAristotle University Of ThessalonikiRan2018 to 2022Enrolled70ConditionsHypertension, Chronic Kidney DiseasesArmsHome Blood Pressure Monitoring
NCT04010344 nacompletednot on this map

Addressing Hypertension Control in Africa (ADHINCRA) Study

TypeinterventionalSponsorJohns Hopkins UniversityRan2019 to 2024Enrolled240ConditionsHypertension, Diabetes, TelemedicineArmsEnhanced Usual Care Group, Usual Care Group
NCT04075045 nacompletednot on this map

Telehealth Intervention for Improved Blood Pressure Control With Targeted Incentives: Using New Technologies and Insights From Behavioral Economics to Increase the Effectiveness of Behavioral Change

TypeinterventionalSponsorWellth Inc.Ran2019 to 2020Enrolled97ConditionsHypertension, Non-Adherence, PatientArmsWellth Smartphone App, Targeted Incentives, Non-Restricted Incentives
NCT04927299 phase3completednot on this map

Confirmatory Study of the Efficacy and Safety of the Combination of Losartan / Chlorthalidone vs Losartan / Hydrochlorothiazide in the Treatment of Patients With Essential Arterial Hypertension

TypeinterventionalSponsorLaboratorios Silanes S.A. de C.V.Ran2022 to 2023Enrolled163ConditionsEssential Arterial HypertensionArmsLosartan/Chlorthalidone in fixed dose, Losartan + hydrochlorothiazide in fixed dose
NCT05744986 unknown statusnot on this map

The Systemic Effects of Transcatheter Renal Artery Sympathetic Denervation Using a Second- Generation Radiofrequency Ablation Catheter: A Multicenter Observational Study.

Typeobservational_patient_registrySponsorChinese University of Hong KongRan2022 to 2025Enrolled100ConditionsHypertension, RenalArmsSYMPICITY Spyral RENAL DENERVATION (RDN) SYSTEMTM
3 · Its place in the literature

Who cites it

3,017 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Phone-based telemonitoring of arterial hypertension versus usual care: the HOROSCOPE study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Trial
  17. Article
  18. Review
  19. Observational
  20. Article

2,957 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Patricia M KearneyDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA.
Megan Whelton
Kristi Reynolds
Paul Muntner
Paul K Whelton
Jiang He

Funding

Clinical Trial of Dietary Protein on Blood PressureR01HL068057 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI HE, JIANG · 2002 to 2006
$2.9M
NHLBI NIH HHS R01 HL68057
6 · The paper itself

Abstract

backgroundReliable information about the prevalence of hypertension in different world regions is essential to the development of national and international health policies for prevention and control of this condition. We aimed to pool data from different regions of the world to estimate the overall prevalence and absolute burden of hypertension in 2000, and to estimate the global burden in 2025.

methodsWe searched the published literature from Jan 1, 1980, to Dec 31, 2002, using MEDLINE, supplemented by a manual search of bibliographies of retrieved articles. We included studies that reported sex-specific and age-specific prevalence of hypertension in representative population samples. All data were obtained independently by two investigators with a standardised protocol and data-collection form.

resultsOverall, 26.4% (95% CI 26.0-26.8%) of the adult population in 2000 had hypertension (26.6% of men [26.0-27.2%] and 26.1% of women [25.5-26.6%]), and 29.2% (28.8-29.7%) were projected to have this condition by 2025 (29.0% of men [28.6-29.4%] and 29.5% of women [29.1-29.9%]). The estimated total number of adults with hypertension in 2000 was 972 million (957-987 million); 333 million (329-336 million) in economically developed countries and 639 million (625-654 million) in economically developing countries. The number of adults with hypertension in 2025 was predicted to increase by about 60% to a total of 1.56 billion (1.54-1.58 billion).

interpretationHypertension is an important public-health challenge worldwide. Prevention, detection, treatment, and control of this condition should receive high priority.

Indexed as

Global HealthAdolescentAdultAgedFemaleHumansHypertensionMaleMiddle AgedPrevalence

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 5 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.