Evidence map›Paper›PMID 15649022›Full record

ArticleJournal of fluorescence2004

The interaction between levofloxacine hydrochloride and DNA mediated by Cu2+.

Gongwu Song, Yu He, Zhaoxia Cai

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gongwu SongFaculty of Chemistry and Material Science, Hubei University, Wuhan 430062, People's Republic of China. songgw@hubu.edu.cn
Yu He
Zhaoxia Cai
Hubei University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Levofloxacin (LEV) is a fluoroquinolone antimicrobial agent. LEV also inhibits DNA synthesis and is bactericidal. The mechanisms of the interaction among LEV, DNA and Cu2+ are studied by fluorescence method. In the paper, the results show that LEV and Cu2+ can form binary complex, and also LEV and DNA can form complex mediated by Cu2+. The composition of the complex is determined. The affects to the reaction are also found.

Indexed as

LevofloxacinAnimalsAnti-Bacterial AgentsCattleCopperDNAIn Vitro TechniquesNucleic Acid DenaturationOfloxacinOsmolar ConcentrationSpectrometry, FluorescenceTemperatureAnti-Bacterial AgentsCopperDNALevofloxacinOfloxacin

Identifiers

PMID15649022
OpenAlexW1980747461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.