Evidence map›Paper›PMID 15642181›Full record

ReviewBreast cancer research : BCR2005

Recent translational research: computational studies of breast cancer.

Michael Retsky, Romano Demicheli, William Hrushesky, John Speer, Douglas Swartzendruber, Robert Wardwell

Abstract readReview
In one paragraph

Review in Breast cancer research : BCR, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. New concepts in breast cancer emerge from analyzing clinical data using numerical algorithms.International journal of environmental research and public health · 2009
    Article
  3. The dynamics of drug resistance: a mathematical perspective.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael RetskyChildren's Hospital and Harvard Medical School, Milan National Cancer Institute, Dorn VA Medical Center, Pepperdine University, Boston, Massachusetts, USA. mretsky@att.net
Romano Demicheli
William Hrushesky
John Speer
Douglas Swartzendruber
Robert Wardwell

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of mathematics--queen of sciences--and the general utility of computers has been used to make important inroads into insight-providing breast cancer research and clinical aids. These developments are in two broad areas. First, they provide useful prognostic guidelines for individual patients based on historic evidence. Second, by suggesting numeric tumor growth laws that are correlated to clinical parameters, they permit development of biologically relevant theories and comparison with patient data to help us understand complex biologic processes. These latter studies have produced many new ideas that are testable in clinical trials. In this review we discuss these developments from a clinical perspective, and ask whether and how they translate into useful tools for patient treatment.

Indexed as

Computational BiologyModels, TheoreticalBreast NeoplasmsClinical Trials as TopicDisease ProgressionFemaleHumansPrognosis

Identifiers

PMID15642181
PMCPMC1064118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.