ReviewNeurotoxicity research2004
Neurotoxins and neurotoxic species implicated in neurodegeneration.
Review in Neurotoxicity research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 93 citations in OpenAlex.
- An Overview of the Relationship Between Occupational Manganese Exposure and Parkinsonism.Cureus · 2022Review
- Prevalence of Parkinsonism Among Foundry Workers in an Automobile Manufacturing Factory in Tehran.Cureus · 2022Article
- In vitro and in vivo evaluation of the neuroprotective activity of Uncaria hirsuta Haviland.Journal of food and drug analysis · 2020Article
- Review
- Nicotine protects against manganese and iron-induced toxicity in SH-SY5Y cells: Implication for Parkinson's disease.Neurochemistry international · 2019Article
- TRPM2 Promotes Neurotoxin MPPMolecular neurobiology · 2018Article
- Multidirectional inhibition of cortico-hippocampal neurodegeneration by kolaviron treatment in rats.Metabolic brain disease · 2017Article
- Clathrin-Dependent Uptake of Paraquat into SH-SY5Y Cells and Its Internalization into Different Subcellular Compartments.Neurotoxicity research · 2017Article
- Protective Effects of Paeoniflorin Against MPP(+)-induced Neurotoxicity in PC12 Cells.Neurochemical research · 2016Article
- Screening for early detection of parkinsonism using a self-administered questionnaire: a cross-sectional epidemiologic study.Neurotoxicology · 2014Article
- Abnormal differentiation of dopaminergic neurons in zebrafish trpm7 mutant larvae impairs development of the motor pattern.Developmental biology · 2014Article
- Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons.Oxidative medicine and cellular longevity · 2014Article
- Olfactory impairment in the rotenone model of Parkinson's disease is associated with bulbar dopaminergic D2 activity after REM sleep deprivation.Frontiers in cellular neuroscience · 2014Article
- RESP18 is involved in the cytotoxicity of dopaminergic neurotoxins in MN9D cells.Neurotoxicity research · 2013Article
- Paeoniflorin, a natural neuroprotective agent, modulates multiple anti-apoptotic and pro-apoptotic pathways in differentiated PC12 cells.Cellular and molecular neurobiology · 2013Article
- Dopaminochrome induces caspase-independent apoptosis in the mesencephalic cell line, MN9D.Journal of neurochemistry · 2012Article
- Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: a new approach for an old neurotoxin.Neurotoxicity research · 2012Article
- Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system.Oxidative medicine and cellular longevity · 2012Article
- Cdk5: mediator of neuronal development, death and the response to DNA damage.Mechanisms of ageing and development · 2011Review
- Single-cell ELISA and flow cytometry as methods for highlighting potential neuronal and astrocytic toxicant specificity.Neurotoxicity research · 2011Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Neurotoxins, in the general sense, represent novel chemical structures which when administered in vivo or in vitro, are capable of producing neuronal damage or neurodegeneration--with some degree of specificity relating to neuronal phenotype or populations of neurons with specific characteristics (i.e., receptor type, ion channel type, astrocyte-dependence, etc.). The broader term 'neurotoxin' includes this categorization but extends the term to include intra- or extracellular mediators involved in the neurodegenerative event, including necrotic and apoptotic factors. Moreover, as it is recognized that astrocytes are essential supportive satellite cells for neurons, and because damage to these cells ultimately affects neuronal function, the term 'neurotoxin' might reasonably be extended to include those chemical species which also adversely affect astrocytes. This review is intended to highlight developments that have occurred in the field of 'neurotoxins' during the past 5 years, including MPTP/MPP+, 6-hydroxydopamine (6-OHDA), methamphetamine; salsolinol; leukoaminochrome-o-semiquinone; rotenone; iron; paraquat; HPP+; veratridine; soman; glutamate; kainate; 3-nitropropionic acid; peroxynitrite anion; and metals (copper, manganese, lead, mercury). Neurotoxins represent tools to help elucidate intra- and extra-cellular processes involved in neuronal necrosis and apoptosis, so that drugs can be developed towards targets that interrupt the processes leading towards neuronal death.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.