Evidence map›Paper›PMID 15639780›Full record

ReviewNeurotoxicity research2004

Tau in neurodegenerative diseases: tau phosphorylation and assembly.

J Avila, M Pérez, F Lim, A Gómez-Ramos, F Hernández, J J Lucas

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurotoxicity research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. ReMAPping the microtubule landscape: How phosphorylation dictates the activities of microtubule-associated proteins.Developmental dynamics : an official publication of the American Association of Anatomists · 2018
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Truncation of tau at E391 promotes early pathologic changes in transgenic mice.Journal of neuropathology and experimental neurology · 2011
    Article
  15. Review
  16. Alzheimer's disease and anesthesia.Frontiers in neuroscience · 2011
    Article
  17. Copper in the brain and Alzheimer's disease.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2010
    Review
  18. Intracellular calcium signalling in Alzheimer's disease.Journal of cellular and molecular medicine · 2010
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J AvilaCentro de Biología Molecular Severo Ochoa (CSIC-UAM). Facultad de Ciencias.Campus de Cantoblanco. Universidad Autónoma de Madrid, 28049 Madrid, Spain. javila@cbm.uam.es
M Pérez
F Lim
A Gómez-Ramos
F Hernández
J J Lucas

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The possible link between tau phosphorylation and tau assembly in these neurodegenerative diseases known as tauopathies is described. Additionally, this link is supported by an in vitro experiment showing the higher capacity of phosphotau to assemble in some specific conditions; and, by a recently reported experiment using a tau transgenic mouse model.

Indexed as

AnimalsCell LineHumansMiceMice, TransgenicNeurodegenerative DiseasesPhosphorylationtau Proteinstau Proteins

Identifiers

PMID15639780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.