ArticleWorld journal of gastroenterology2005
Potential oxidative stress in children with chronic constipation.
Article in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 32 citations in OpenAlex.
- Antioxidant and Laxative Effects of Methanol Extracts of Green Pine Cones (Antioxidants (Basel, Switzerland) · 2024Article
- Effects of Functional Red Pine Seed Direct-Drinking Oil on Constipation and Intestinal Barrier Function in Mice.Antioxidants (Basel, Switzerland) · 2024Article
- The relationship between oxidative balance scores and chronic diarrhea and constipation: a population-based study.BMC public health · 2024Article
- Association between dietary vitamin E intake and constipation: NHANES 2005-2010.Frontiers in nutrition · 2024Article
- Risk relationship between leukocyte telomere length and constipation: a Mendelian randomization study.Frontiers in medicine · 2023Article
- Antioxidant activity and laxative effects of tannin-enriched extract of Ecklonia cava in loperamide-induced constipation of SD rats.PloS one · 2021Article
- Probiotics decrease depressive behaviors induced by constipation via activating the AKT signaling pathway.Metabolic brain disease · 2018Article
- Redox theory of aging: implications for health and disease.Clinical science (London, England : 1979) · 2017Review
- Vinblastine, an anticancer drug, causes constipation and oxidative stress as well as others disruptions in intestinal tract in rat.Toxicology reports · 2017Article
- Bowel movement frequency, oxidative stress and disease prevention.Molecular and clinical oncology · 2016Article
- Dose-dependent Action ofDose-response : a publication of International Hormesis SocietyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the potential oxidative stress in children with chronic constipation and to explore its mechanisms.
methodsSeventy children with chronic constipation and 70 age- and sex-matched healthy children were enrolled in a randomized controlled study. Plasma levels of vitamins C and E, activities of superoxide dismutase and catalase and lipoperoxide level in erythrocytes were determined by spectrophotometry.
resultsCompared with healthy children whose vitamin C, vitamin E, superoxide dismutase, catalase and lipoperoxide were 58.35+/-14.42 micromol/L, 27.15+/-6.55 micromol/L, 2 206+/-171 U/(g.Hb), 327.3+/-82.2 K/(g.Hb) and 19.18+/-4.27 nmol/(g.Hb) respectively, the levels of vitamin C, vitamin E, the activity of superoxide dismutase, and catalase in the children with chronic constipation significantly decreased [46.59+/-11.51 micromol/L, 20.65+/-4.80 micromol/L, 1943+/-147 U/(g.Hb) and 269.3+/-67.8 K/(g.Hb), respectively P<0.01], while the lipoperoxide significantly increased [25.22+/-5.01 nmol/(g.Hb), P<0.01]. With a prolonged course of disease, the levels of vitamin C, vitamin E, the activity of superoxide dismutase and catalase in the children with chronic constipation gradually decreased, while the level of lipoperoxide gradually increased.
conclusionChronic constipation can cause potential oxidative stress in children.
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