Evidence map›Paper›PMID 15634963›Full record

ArticleJournal of clinical microbiology2005

Interlaboratory comparison of PCR-based identification and genogrouping of Neisseria meningitidis.

Muhamed-Kheir Taha, Jean-Michel Alonso, Mary Cafferkey, Dominique A Caugant, Stuart C Clarke, Mathew A Diggle, Andrew Fox, Matthias Frosch, Stephen J Gray, Malcolm Guiver and 12 more

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Prevalence ofOpen forum infectious diseases · 2025
    Article
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  3. Genetic and Antigenic Diversity ofPathogens (Basel, Switzerland) · 2025
    Article
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  7. Suspected Materno-Fetal Transmission ofOpen forum infectious diseases · 2020
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. COMPARISON OF METHODS TO IDENTIFY Neisseria meningitidis IN ASYMPTOMATIC CARRIERS.Revista do Instituto de Medicina Tropical de Sao Paulo · 2016
    Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Muhamed-Kheir TahaNeisseria Unit and the French National Reference Center for Meningococci, Institut Pasteur, Paris, France. mktaha@pasteur.fr
Jean-Michel Alonso
Mary Cafferkey
Dominique A Caugant
Stuart C Clarke
Mathew A Diggle
Andrew Fox
Matthias Frosch
Stephen J Gray
Malcolm Guiver
Sigrid Heuberger
Jitka Kalmusova
Konstantinos Kesanopoulos
Anne-Marie Klem
Paula Kriz
John Marsh
Paula Mölling
Karen Murphy
Per Olcén
Oumar Sanou
Georgina Tzanakaki
Ulrich Vogel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty clinical samples (18 cerebrospinal fluid samples and 2 articular fluid samples) were sent to 11 meningococcus reference centers located in 11 different countries. Ten of these laboratories are participating in the EU-MenNet program (a European Union-funded program) and are members of the European Monitoring Group on Meningococci. The remaining laboratory was located in Burkina Faso. Neisseria meningitidis was sought by detecting several meningococcus-specific genes (crgA, ctrA, 16S rRNA, and porA). The PCR-based nonculture method for the detection of N. meningitidis gave similar results between participants with a mean sensitivity and specificity of 89.7 and 92.7%, respectively. Most of the laboratories also performed genogrouping assays (siaD and mynB/sacC). The performance of genogrouping was more variable between laboratories, with a mean sensitivity of 72.7%. Genogroup B gave the best correlation between participants, as all laboratories routinely perform this PCR. The results for genogroups A and W135 were less similar between the eight participating laboratories that performed these PCRs.

Indexed as

LaboratoriesAdolescentAdultBurkina FasoChildChild, PreschoolDNA, BacterialEuropean UnionFemaleGenotypeHumansInfantMaleMeningitis, MeningococcalMeningococcal InfectionsNeisseria meningitidisDNA, Bacterial

Identifiers

PMID15634963
PMCPMC540131

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.