Evidence map›Paper›PMID 15634745›Full record

ArticleJournal of medical ethics2005

Informed consent should be obtained from patients to use products (skin substitutes) and dressings containing biological material.

S Enoch, H Shaaban, K W Dunn

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical ethics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 111 citations in OpenAlex.

  1. Skin grafting for venous leg ulcers.The Cochrane database of systematic reviews · 2013
    Pooled it
  2. Venous leg ulcers.BMJ clinical evidence · 2011
    Pooled it
  3. Venous leg ulcers.BMJ clinical evidence · 2008
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Uninformed Origins: Should We Be Advising Parents on the Source of Medicines and Therapies?Health care analysis : HCA : journal of health philosophy and policy · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Ethics and Policy for Bioprinting.Methods in molecular biology (Clifton, N.J.) · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. An audit of consent for allograft use in elective orthopaedic surgery.Annals of the Royal College of Surgeons of England · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

S EnochDepartment of Plastic Surgery, University Hospitals of South Manchester, UK. enochstuart@hotmail.com
H Shaaban
K W Dunn
Alder Hey Children's Hospital · GBUniversity of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiological products (tissue engineered skin, allograft and xenograft, and biological dressings) are widely used in the treatment of burns, chronic wounds, and other forms of acute injury. However, the religious and ethical issues, including consent, arising from their use have never been addressed in the medical literature.

aimsThis study was aimed to ascertain the views of religious leaders about the acceptability of biological products and to evaluate awareness among healthcare professionals about their constituents.

methodsThe religious groups that make up about 75% of the United Kingdom population were identified and a questionnaire on 11 biological products was sent to its leaders. Another questionnaire concerning 17 products (11 biological and 6 synthetic dressings) was sent to 100 healthcare professionals working in seven specialist units in the UK.

resultsAll religious leaders (100% response rate) replied, some after consultation with international bodies. Among them, 77% said that patients should be informed of the constituents of the biological products and consent obtained. Some leaders expressed concerns about particular products including the transmission of viral and prion diseases, cruelty to animals, and material derived from neonates. None of the healthcare professionals (73% response rate) surveyed knew the constituents of all the products correctly.

conclusionIgnoring religious sensitivities and neglecting consent in the usage of biological products could have very serious implications, including litigation. Hospitals and manufacturers should take immediate measures to enlighten healthcare professionals of the constituents of these products so that they can obtain informed consent from patients.

Indexed as

Biocompatible MaterialsReligion and MedicineAttitude to HealthBandagesHealth Knowledge, Attitudes, PracticeHealth PersonnelHumansInformed ConsentSkin, ArtificialUnited KingdomBiocompatible MaterialsEmpirical ApproachHealth Care and Public HealthReligious Approach

Identifiers

PMID15634745
PMCPMC1734000
OpenAlexW2164516616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.