ArticleAmerican journal of medical genetics. Part A2005
Idiopathic talipes equinovarus (ITEV) (clubfeet) in Texas.
Article in American journal of medical genetics. Part A, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 63 citations in OpenAlex.
- Pregnancy outcomes in HIV-infected women receiving long-term isoniazid prophylaxis for tuberculosis and antiretroviral therapy.Infectious diseases in obstetrics and gynecology · 2013Trial
- Isolated clubfoot in the Northern Territory of Australia: birth prevalence and population description.International journal of epidemiology · 2025Article
- Risk Factors of Idiopathic Congenital Clubfoot in the South of Vietnam: A Hospital-Based Study.Cureus · 2025Article
- The Incidence of Clubfoot in the Czech Republic: A Nationwide Epidemiological Study from 2000 to 2014.Children (Basel, Switzerland) · 2023Article
- Analysis OF C677T polymorphism in methylene tetrahydrofolate reductase (MTHFR) gene as a risk factor for congenital talipes equino varus (CTEV).Journal of clinical orthopaedics and trauma · 2021Article
- Are incidence and severity of clubfoot related to the season of birth?World journal of pediatrics : WJP · 2016Article
- Functional Assessment of Clubfoot Associated HOXA9, TPM1, and TPM2 Variants Suggests a Potential Gene Regulation Mechanism.Clinical orthopaedics and related research · 2016Article
- Association between maternal age at conception and risk of idiopathic clubfoot.Acta orthopaedica · 2016Article
- Apoptotic genes expression in placenta of clubfoot-like fetus pregnant rats.International journal of clinical and experimental pathology · 2014Article
- Descriptive epidemiology of idiopathic clubfoot.American journal of medical genetics. Part A · 2013Article
- Descriptive epidemiology of clubfoot in Peru: a clinic-based study.The Iowa orthopaedic journal · 2013Article
- Studies of TBX4 and chromosome 17q23.1q23.2: an uncommon cause of nonsyndromic clubfoot.American journal of medical genetics. Part A · 2012Article
- Congenital talipes equinovarus: an epidemiological study in Sicily.Acta orthopaedica · 2012Article
- Descriptive epidemiology of clubfoot in Vietnam: a clinic-based study.The Iowa orthopaedic journal · 2012Article
- Variants in genes that encode muscle contractile proteins influence risk for isolated clubfoot.American journal of medical genetics. Part A · 2011Article
- Article
- Smoking, the xenobiotic pathway, and clubfoot.Birth defects research. Part A, Clinical and molecular teratology · 2011Article
- Epidemiology of congenital idiopathic talipes equinovarus in Iowa, 1997-2005.American journal of medical genetics. Part A · 2010Article
- Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.American journal of medical genetics. Part A · 2009Article
- Pedigree analysis and epidemiological features of idiopathic congenital talipes equinovarus in the United Kingdom: a case-control study.BMC musculoskeletal disorders · 2007Article
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6 authors at 2 institutions in 1 country.
Funding
Abstract
Idiopathic talipes equinovarus (ITEV) is the most common form of clubfoot with a birth prevalence of 1 per 1,000 births. Serial casting and surgical correction impose a substantial financial burden on families and the health care system. While the etiology of ITEV is considered to be complex, the causes remain elusive. Genetic, maternal, and environmental factors have been suggested to play an etiologic role. This study was undertaken to determine the prevalence of ITEV and define maternal and environmental factors associated with ITEV in Texas from 1996 to 1999. Data on 682 cases of nonsyndromic ITEV were compared with all births (n = 923,543) in Texas during the same period. The overall prevalence and prevalence odds ratios (PORs) were calculated for gender, year of birth, public health region (PHR), race, maternal age, education, folic acid fortification, and parity. The overall prevalence of ITEV was 0.74/1,000 or 1/1,354 live births. Adjusted PORs were similar among blacks and US and foreign-born Hispanics (POR = 0.92, 95% CI = 0.69-1.21; POR = 0.99, 95% CI = 0.79-1.25; and POR = 0.94, 95% CI = 0.74-1.19), respectively, compared to whites. College education and higher parity were significantly associated with a lower risk of giving birth to offspring with ITEV. Babies born after folic acid fortification of grains had a very small decrease in ITEV that may be due to chance.
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