Evidence map›Paper›PMID 1563097›Full record

ArticleClinical and experimental immunology1992

Specific recognition pattern of IgM and IgG antibodies produced in the course of experimental paracoccidioidomycosis.

C A Vaz, D W Mackenzie, V M Hearn, Z P Camargo, L M Singer-Vermes, E Burger, V L Calich

Abstract read
In one paragraph

Article in Clinical and experimental immunology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C A VazDepartment of Immunology, Universidade de Sao Paulo, Brazil.
D W Mackenzie
V M Hearn
Z P Camargo
L M Singer-Vermes
E Burger
V L Calich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific IgM and IgG responses to Paracoccidioides brasiliensis produced in resistant and susceptible mice during experimental paracoccidioidomycosis were examined by the immunoblotting procedure. Sera from infected mice recognized 51 antigen bands with apparent molecular masses from 8 to 86 kD. Sixteen of these were defined as major antigen bands because of almost universal presence of antibodies to them, and their intense staining. All sera, including those from normal control mice, tested for both IgM and IgG antibody reacted with the major E antigen which appeared as a large diffuse band from 43 to 47 kD. Comparisons between resistant and susceptible mice showed some significant differences in IgM responses to many antigen bands. While IgG responses were quite similar for both strains, differences were apparent in the response to the antigens at 62 and 68 kD.

Indexed as

AnimalsAntibodies, FungalAntigens, FungalImmunoglobulin GImmunoglobulin MMiceMolecular WeightParacoccidioidomycosisAntibodies, FungalAntigens, FungalImmunoglobulin GImmunoglobulin M

Identifiers

PMID1563097
PMCPMC1554371

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.