ArticlePLoS biology2005
A gradual process of recombination restriction in the evolutionary history of the sex chromosomes in dioecious plants.
Article in PLoS biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers.
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108 citing papers in PubMed, 243 citations in OpenAlex.
- Genome assemblies of the liverwort Blasia pusilla uncover a well-defined pseudoautosomal region on homomorphic UV sex chromosomes.Genome biology · 2026Article
- Whole-genome sequencing reveals a possible molecular basis of sex determination in the dioecious wild yam Dioscorea tokoro.PLoS genetics · 2026Article
- TheScience (New York, N.Y.) · 2025Article
- Chromosome-Level Genome Assembly for the Angiosperm Silene conica.Genome biology and evolution · 2023Article
- The origin and evolution of sex chromosomes, revealed by sequencing of the Silene latifolia female genome.Current biology : CB · 2023Article
- Parallel Evolution of Sex-Linked Genes across XX/XY and ZZ/ZW Sex Chromosome Systems in the FrogGenes · 2023Article
- Onset and stepwise extensions of recombination suppression are common in mating-type chromosomes of Microbotryum anther-smut fungi.Journal of evolutionary biology · 2022Article
- Heterogeneous Evolution of Sex Chromosomes in the Torrent Frog GenusInternational journal of molecular sciences · 2022Article
- The evolution of huge Y chromosomes inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Tempo of Degeneration Across Independently Evolved Nonrecombining Regions.Molecular biology and evolution · 2022Article
- Schistosome W-Linked Genes Inform Temporal Dynamics of Sex Chromosome Evolution and Suggest Candidate for Sex Determination.Molecular biology and evolution · 2021Article
- The timing of genetic degeneration of sex chromosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Recombination suppression and evolutionary strata around mating-type loci in fungi: documenting patterns and understanding evolutionary and mechanistic causes.The New phytologist · 2021Review
- Divergence and Remarkable Diversity of the Y Chromosome in Guppies.Molecular biology and evolution · 2021Article
- Discovery of SNPs in important legumes through comparative genome analysis and conversion of SNPs into PCR-based markers.Journal of genetics · 2021Article
- Article
- Evidence for Dosage Compensation inGenes · 2020Article
- Genome assembly of the basket willow, Salix viminalis, reveals earliest stages of sex chromosome expansion.BMC biology · 2020Article
- Guppy Y Chromosome Integrity Maintained by Incomplete Recombination Suppression.Genome biology and evolution · 2020Article
- The Location of the Pseudoautosomal Boundary inGenes · 2020Article
48 more citing papers are in PubMed but not listed here.
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10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To help understand the evolution of suppressed recombination between sex chromosomes, and its consequences for evolution of the sequences of Y-linked genes, we have studied four X-Y gene pairs, including one gene not previously characterized, in plants in a group of closely related dioecious species of Silene which have an X-Y sex-determining system (S. latifolia, S. dioica, and S. diclinis). We used the X-linked copies to build a genetic map of the X chromosomes, with a marker in the pseudoautosomal region (PAR) to orient the map. The map covers a large part of the X chromosomes--at least 50 centimorgans. Except for a recent rearrangement in S. dioica, the gene order is the same in the X chromosomes of all three species. Silent site divergence between the DNA sequences of the X and Y copies of the different genes increases with the genes' distances from the PAR, suggesting progressive restriction of recombination between the X and Y chromosomes. This was confirmed by phylogenetic analyses of the four genes, which also revealed that the least-diverged X-Y pair could have ceased recombining independently in the dioecious species after their split. Analysis of amino acid replacements vs. synonymous changes showed that, with one possible exception, the Y-linked copies appear to be functional in all three species, but there are nevertheless some signs of degenerative processes affecting the genes that have been Y-linked for the longest times. Although the X-Y system evolved quite recently in Silene (less than 10 million years ago) compared to mammals (about 320 million years ago), our results suggest that similar processes have been at work in the evolution of sex chromosomes in plants and mammals, and shed some light on the molecular mechanisms suppressing recombination between X and Y chromosomes.
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