Evidence map›Paper›PMID 15629945›Full record

ArticleJournal of bacteriology2005

Identification and complementation of a mutation associated with loss of Mycoplasma pneumoniae virulence-specific proteins B and C.

Robert H Waldo, Jarrat L Jordan, Duncan C Krause

Abstract read
In one paragraph

Article in Journal of bacteriology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Robert H WaldoDepartment of Microbiology, 523 Biological Sciences Bldg., University of Georgia, Athens, GA 30602, USA.
Jarrat L Jordan
Duncan C Krause

Funding

GENETIC ANALYSIS OF MYCOPLASMA PNEUMONIAE CELL ADHERENCER01AI023362 · NIAID · UNIVERSITY OF GEORGIA (UGA) · PI KRAUSE, DUNCAN C · 1986 to 2008
$2.4M
NIAID NIH HHS AI23362NIAID NIH HHS R01 AI023362
6 · The paper itself

Abstract

A mutation in gene MPN142 (orf6) was identified in the Mycoplasma pneumoniae cytadherence mutant III-4. MPN142 encodes virulence-specific proteins P90 and P40 (proteins B and C, respectively). Analysis of MPN142 in a cytadhering revertant and complementation using a recombinant wild-type allele confirmed the role of this mutation in the cytadherence defect.

Indexed as

MutationBacterial AdhesionBacterial ProteinsDNA Mutational AnalysisGenetic Complementation TestMycoplasma pneumoniaeVirulence FactorsBacterial ProteinsVirulence Factors

Identifiers

PMID15629945
PMCPMC543562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.