ArticleRheumatology international2005
Active disease during pregnancy is associated with poor foetal outcome in Indian patients with systemic lupus erythematosus.
Article in Rheumatology international, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Systemic Lupus Erythematosus in Pregnancy.Medical sciences (Basel, Switzerland) · 2025Pooled it
- Preconception care: screening and management of chronic disease and promoting psychological health.Reproductive health · 2014Pooled it
- A systematic review and meta-analysis of pregnancy outcomes in patients with systemic lupus erythematosus and lupus nephritis.Clinical journal of the American Society of Nephrology : CJASN · 2010Pooled it
- Evaluation of red blood cell distribution width-platelet ratio as a predictor of adverse pregnancy outcomes and disease severity in systemic lupus erythematosus.Clinical rheumatology · 2022Article
- Poor maternal and foetal outcomes in women with systemic sclerosis: an interview-based study at a tertiary centre.Rheumatology international · 2021Observational
- Article
- Adverse pregnancy outcomes in adolescents and young women with systemic lupus erythematosus: a national estimate.Pediatric rheumatology online journal · 2018Article
- Preeclampsia as a Manifestation of New-Onset Systemic Lupus Erythematosus during Pregnancy: A Case-Based Literature Review.AJP reports · 2016Article
- Lupus nephritis is associated with poor pregnancy outcomes in pregnant SLE patients in Cape Town: a retrospective analysis.The Pan African medical journal · 2015Article
- Preconception care: delivery strategies and packages for care.Reproductive health · 2014Review
- Systemic lupus erythematosus pregnancies: the Sarawak experience and review of lupus pregnancies in Asia.Rheumatology international · 2011Article
- A comparative study of pregnancy outcomes and menstrual irregularities in northern Indian patients with systemic lupus erythematosus and rheumatoid arthritis.Rheumatology international · 2010Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a paucity of data regarding the outcome of pregnancy from the Indian subcontinent. Therefore, we decided to analyse the outcome of pregnancy in our cohort of mothers with systemic lupus erythematosus (SLE). Data regarding pregnancies after onset of disease in patients with SLE was analysed in terms of number of pregnancies, effect of pregnancy on disease activity and effect of disease such as organ involvement, presence of anticardiolipin and anti-Ro antibodies, on the outcome of pregnancy. Fifty-two pregnancies occurred in 31 patients. Thirty-one and 21 pregnancies occurred when the disease was inactive and active, respectively. Excluding the 11 induced abortions, the live birth rate was 82.6% in the inactive group and 27.7% in the active group. Foetal loss was mainly due to 12 spontaneous abortions. There were three stillbirths and two neonatal deaths. Disease flare occurred only in the active group, one during pregnancy and two post-partum, one of which resulted in the death of the patient. The presence of antibodies to cardiolipin and to Ro/La was not associated with adverse outcome. Thus, the live birth rate in developing countries in SLE mothers is worse compared with developed countries. Active disease during pregnancy is significantly associated with increased foetal loss.
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