Evidence map›Paper›PMID 15619644›Full record

ArticlePathology oncology research : POR2004

Establishment and characterization of a human large cell lung cancer cell line with neuroendocrine differentiation.

Sedigheh Sharifzadeh, S Mohammad Owji, Abdul Mohammad Pezeshki, Zahra Malek-Hoseini, Perikala Vijayananda Kumar, Sied Mohammad Ali Ghayumi, Abbas Ghaderi

Abstract read
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Article in Pathology oncology research : POR, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sedigheh SharifzadehDepartment of Immunology, Shiraz University of Medical Sciences, Shiraz, Iran.
S Mohammad Owji
Abdul Mohammad Pezeshki
Zahra Malek-Hoseini
Perikala Vijayananda Kumar
Sied Mohammad Ali Ghayumi
Abbas Ghaderi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Characterization of a human lung cancer cell line is reported. This cell line was established from a patient referred to Nemazi Hospital of Shiraz University of Medical Sciences with a diagnosis of poorly differentiated carcinoma. Sterile sample from peritoneal effusion was taken and immediately cultured in RPMI-1640 medium containing 20% FBS, at 37 degrees C with 5% CO2. This cell line has been in continuous culture for more than one year and has been named as Mehr-80. Several features of the cell line were investigated, including growth characteristics, electron microscopic features, cloning efficiency in soft agar, expression of various antigenic markers, chromosomal and DNA analysis. On the basis of morphological and immunohistochemical analysis of Mehr-80, it is possible to conclude that this cell line is characterized by features similar to those reported for large cell carcinoma with neuroendocrine differentiation (LCCND). This cell line will be a valuable in vitro tool for further studies on lung cancers.

Indexed as

Cell Line, TumorCarcinoma, Large CellCell DivisionHumansImmunohistochemistryLung NeoplasmsMicroscopy, Electron, Transmission

Identifiers

PMID15619644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.