ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2005
Epidemiology and antifungal susceptibility of Candida species isolated from blood: results of a 2-year multicentre study in Spain.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27 citing papers in PubMed, 121 citations in OpenAlex.
- Management of Intra-Abdominal Candidiasis in Intensive Care Setting: A Narrative Review.Journal of fungi (Basel, Switzerland) · 2025Review
- Emergence and circulation of azole-resistantFrontiers in cellular and infection microbiology · 2023Article
- Surveillance of Antifungal Resistance in Candidemia Fails to Inform Antifungal Stewardship in European Countries.Journal of fungi (Basel, Switzerland) · 2022Article
- The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2019Article
- Potent and Synergistic Extract Combinations fromMedicines (Basel, Switzerland) · 2015Article
- Surveillance study of species distribution, antifungal susceptibility and mortality of nosocomial candidemia in a tertiary care hospital in China.BMC infectious diseases · 2013Article
- Effect of statin use on outcomes of adults with candidemia.PloS one · 2013Article
- Epidemiology and echinocandin susceptibility of Candida parapsilosis sensu lato species isolated from bloodstream infections at a Spanish university hospital.The Journal of antimicrobial chemotherapy · 2012Article
- Neonatal intensive care unit candidemia: epidemiology, risk factors, outcome, and critical review of published case series.Mycopathologia · 2012Article
- Epidemiology and antifungal susceptibility of bloodstream fungal isolates in pediatric patients: a Spanish multicenter prospective survey.Journal of clinical microbiology · 2011Article
- Prospective multicenter study of the epidemiology, molecular identification, and antifungal susceptibility of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis isolated from patients with candidemia.Antimicrobial agents and chemotherapy · 2011Article
- First reported case of catheter-related fungemia due to Candida mengyuniae.Journal of clinical microbiology · 2011Article
- Characterization of Candida species from different populations in Taiwan.Mycopathologia · 2011Article
- National surveillance of fungemia in Denmark (2004 to 2009).Journal of clinical microbiology · 2011Article
- Candidemia distribution, associated risk factors, and attributed mortality at a university-based medical center.Puerto Rico health sciences journal · 2010Article
- Identification of a Candida parapsilosis strain producing extracellular serine peptidase with keratinolytic activity.Mycopathologia · 2010Article
- In vitro activities of echinocandins against Candida krusei determined by three methods: MIC and minimal fungicidal concentration measurements and time-kill studies.Antimicrobial agents and chemotherapy · 2009Article
- Review
- A first Portuguese epidemiological survey of fungaemia in a university hospital.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2008Article
- One year prospective survey of Candida bloodstream infections in Scotland.Journal of medical microbiology · 2007Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study, included in the prospective survey of candidaemia in Europe supported by the European Confederation of Medical Mycology, presents the epidemiological and antifungal susceptibility results of 290 cases of candidaemia (80 in children <15 years old) reported from September 1997 to August 1999 by 19 Spanish hospitals. Presence of an intravenous catheter and previous antibiotic therapy were the most frequent risk factors. The percentages of the four most common species isolated (adults/children) were as follows: Candida albicans (46/36.2), C. parapsilosis (21.9/50), C. tropicalis (12.8/3.75), and C. glabrata (10.1/5). As initial therapy, fluconazole was preferred in adults (54%) and liposomal amphotericin B in children (58%). The 30-day mortality rate was 40.6%, and the species most frequently associated with a fatal outcome was C. krusei (60%). The rates of susceptibility to antifungal agents were as follows: amphotericin B, 91%; flucytosine, 99%; fluconazole, 93.6%; itraconazole, 87.4%; and voriconazole, 92%. These results provide baseline data for future epidemiological and susceptibility studies and for evaluating the impact of new antifungal agents on the distribution of species and the mortality rates associated with candidaemia in Spain.
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