Evidence map›Paper›PMID 15617269›Full record

ReviewJournal of fluorescence2004

Ophthalmic glucose monitoring using disposable contact lenses--a review.

Ramachandram Badugu, Joseph R Lakowicz, Chris D Geddes

Abstract readReview
In one paragraph

Review in Journal of fluorescence, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Observational
  12. Contact-Lens Biosensors.Sensors (Basel, Switzerland) · 2018
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. A disposable tear glucose biosensor-part 1: design and concept testing.Journal of diabetes science and technology · 2010
    Article
  18. Article
  19. Wavelength-ratiometric and colorimetric probes for glucose determination.Dyes and pigments : an international journal · 2006
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ramachandram BaduguDepartment of Biochemistry and Molecular Biology, Center for Fluorescence Spectroscopy, University of Maryland School of Medicine, 725 West Lombard Street, Baltimore, Maryland 21201, USA.
Joseph R Lakowicz
Chris D Geddes
University of Maryland, Baltimore · US

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 1993 to 2006
$7.4M
NCRR NIH HHS P41 RR008119NCRR NIH HHS RR-08119
6 · The paper itself

Abstract

We have developed a range of disposable and colorless tear glucose sensing contact lenses, using off-the-shelf lenses embedded with new water soluble, highly fluorescent and glucose sensitive boronic acid containing fluorophores. The new lenses are readily able to track tear glucose levels and therefore blood glucose levels, which are ideally suited for potential use by diabetics. The fluorescence responses from the lenses can be monitored using simple excitation and emission detection devices. The novelty of our approach is two fold. Firstly, the notion of sensing extremely low glucose concentrations in tears, which track blood levels, by our contact lens approach, and secondly, the unique compatibility of our new glucose signaling probes with the internal mildly acidic contact lens environment. The new lenses are therefore ideal for the non-invasive and continuous monitoring of tear glucose, with about 15-min response time, and a measured shelf life in excess of 3 months. In this review article, we show that fluorescence based signaling using plastic disposable lenses, which have already been industrially optimized with regard to vision correction and oxygen/analyte permeability etc, may a notable alternative to invasive and random finger pricking, the most widely used glucose monitoring technology by diabetics.

Indexed as

Contact LensesAlgorithmsAnionsBoronic AcidsFluorescent DyesFluorometryFructoseGlucoseHalogensHumansHydrogen-Ion ConcentrationMonitoring, PhysiologicQuinolinium CompoundsSpectrometry, FluorescenceSpectrophotometryTearsAnionsBoronic AcidsFluorescent DyesFructoseGlucoseHalogensQuinolinium Compounds

Identifiers

PMID15617269
PMCPMC4904789
OpenAlexW2112780055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.