Evidence map›Paper›PMID 15617260›Full record

ArticleJournal of fluorescence2004

Evaluation of pyranine derivatives in boronic acid based saccharide sensing: significance of charge interaction between dye and quencher in solution and hydrogel.

Frank E Cappuccio, Jeff T Suri, David B Cordes, Ritchie A Wessling, Bakthan Singaram

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 52 citations in OpenAlex.

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  11. A glucose-sensing contact lens: from bench top to patient.Current opinion in biotechnology · 2005
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Frank E CappuccioDepartment of Chemistry and Biochemistry, University of California at Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.
Jeff T Suri
David B Cordes
Ritchie A Wessling
Bakthan Singaram
University of California, Santa Cruz · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an ongoing program to synthesize a glucose sensing polymer that could be used for real time glucose monitoring in vivo, we have been exploring the use of boronic acid functional viologens as glucose responsive quenchers for fluorescent dyes. The present study focuses on the effect of ionic interactions between pyranine or its various sulfonamide derivatives and the viologen quenchers. Dyes bearing anionic groups were quenched more efficiently when compared to dyes with nonionic substituents. The anionic dyes in conjunction with the cationic quenchers exhibited a broader range of glucose response both in solution and when immobilized in a hydrogel. The interaction of glucose with the sensing components was similar whether they are soluble or immobilized.

Indexed as

AlgorithmsArylsulfonatesBiosensing TechniquesBlood GlucoseBoron CompoundsBoronic AcidsFluorescent DyesGlucoseHumansHydrogel, Polyethylene Glycol DimethacrylateMolecular StructureMonitoring, PhysiologicMonosaccharidesSpectrometry, FluorescenceViologensArylsulfonatesBlood GlucoseBoron CompoundsBoronic AcidsFluorescent DyesGlucoseHydrogel, Polyethylene Glycol DimethacrylateMonosaccharidespyranineViologens

Identifiers

PMID15617260
OpenAlexW2092729728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.