ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2005
Method for detection of respiratory viruses in the sputa of patients with cystic fibrosis.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Acute Pulmonary Exacerbation Phenotypes in Patients with Cystic Fibrosis.Annals of the American Thoracic Society · 2022Article
- Respiratory Viral Infections in Chronic Lung Diseases.Clinics in chest medicine · 2017Review
- Influenza vaccination in children at high risk of respiratory disease.Therapeutic advances in vaccines · 2013Article
- Spectrum of viral infections in patients with cystic fibrosis.European journal of microbiology & immunology · 2012Review
- Respiratory viruses in children with cystic fibrosis: viral detection and clinical findings.Influenza and other respiratory viruses · 2012Article
- The changing microbial epidemiology in cystic fibrosis.Clinical microbiology reviews · 2010Review
- The role of respiratory viruses in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2008Article
- Ten years of viral and non-bacterial serology in adults with cystic fibrosis.Epidemiology and infection · 2008Article
- Cystic Fibrosis: The Mechanisms of Pathogenesis of an Inherited Lung Disorder.Drug discovery today. Disease mechanisms · 2007Article
- Effective mucus clearance is essential for respiratory health.American journal of respiratory cell and molecular biology · 2006Review
- Viral respiratory infections in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2005Review
- Bronchiectasis exacerbations: The role of atypical bacteria, respiratory syncytial virus and pulmonary function tests.Canadian respiratory journalObservational
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the role of respiratory viruses in lung exacerbations of patients with cystic fibrosis has been hampered by the difficulty of detecting viruses in viscous sputum specimens, a multiplex reverse transcriptase PCR (RT-PCR) assay combined with colorimetric amplicon detection was tested for the identification of seven common respiratory viruses in the sputa of cystic fibrosis patients. Of 52 sputa from 38 patients, 12 (23%) samples from 12 patients were positive for a respiratory virus (4 for influenza B, 3 for parainfluenza 1, 3 for influenza A and 2 for respiratory syncytial virus). These results suggest that the RT-PCR method carried out on sputum may provide a convenient means of investigating the role of virus infection in lung exacerbations of cystic fibrosis patients.
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