ArticleAntimicrobial agents and chemotherapy2005
Streptococcus pyogenes pharyngeal isolates with reduced susceptibility to ciprofloxacin in Spain: mechanisms of resistance and clonal diversity.
Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Identification and Characterization of Fluoroquinolone Non-susceptibleFrontiers in microbiology · 2018Article
- Characterization of levofloxacin non-susceptible clinical Streptococcus pyogenes isolated in the central part of Italy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014Article
- Effect of subinhibitory concentrations of fluoroquinolones on biofilm production by clinical isolates of Streptococcus pyogenes.The Indian journal of medical research · 2013Article
- Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal.Antimicrobial agents and chemotherapy · 2010Article
- Fluoroquinolone resistance in Streptococcus dysgalactiae subsp. equisimilis and evidence for a shared global gene pool with Streptococcus pyogenes.Antimicrobial agents and chemotherapy · 2010Article
- Drug resistance in community-acquired respiratory tract infections: role for an emerging antibacterial.Infection and drug resistance · 2010Article
- Prevalence and clonal characterization of Streptococcus pyogenes clinical isolates with reduced fluoroquinolone susceptibility in Spain.Antimicrobial agents and chemotherapy · 2010Article
- An intrinsic pattern of reduced susceptibility to fluoroquinolones in pediatric isolates of Streptococcus pyogenes.Diagnostic microbiology and infectious disease · 2008Article
- Sequence type and emm type diversity in Streptococcus pyogenes isolates causing invasive disease in Norway between 1988 and 2003.Journal of clinical microbiology · 2008Article
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Authors and funding
8 authors.
Funding
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Abstract
A survey of emm gene sequences and an analysis of the pulsed-field electrophoretic profiles of 30 Streptococcus pyogenes isolates with reduced susceptibilities to ciprofloxacin detected the prevalence of isolates with emm type 6 and considerable genetic diversity among isolates. The mechanism of ciprofloxacin resistance in these isolates was based on point mutations in topoisomerase IV subunit C encoded by parC, mainly replacement of serine-79 by alanine.
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