Evidence map›Paper›PMID 15614547›Full record

ArticleJournal of mathematical biology2005

Wave speeds of density dependent Nagumo diffusion equations--inspired by oscillating gap-junction conductance in the islets of Langerhans.

Morten Gram Pedersen

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of mathematical biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Morten Gram PedersenDepartment of Mathematics, The Technical University of Denmark, 2800 Kgs. Lyngby, Denmark. m.g.pedersen@mat.dtu.dk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The equation ut = (D(u)ux)x + f(u) arises in several biological examples and is known to have wave solutions for appropriate D and f. We give here a new formula for finding an approximation to the wave speed, relevant for comparing experiments with model simulations. This is done in details for the simple example D(u) = u + k and an N-shaped f, derived from a model of coupled pancreatic beta-cells, where the coupling conductance follows the electrical activity as it is found in experiments. On the way, we claim that the wave speed does not depend on the parameter g(K,ATP), mimicking the glucose concentration in the islet, in sharp contrast to the claim set forth in the article by Aslanidi et al.

Indexed as

Models, BiologicalCalciumComputer SimulationElectric ConductivityGap JunctionsGlucoseHumansIslets of LangerhansPotassium ChannelsCalciumGlucosePotassium Channels

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.