Relevance of apoptin's integrity for its functional behavior.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Semisynthesis reveals apoptin as a tumour-selective protein prodrug that causes cytoskeletal collapse.Chemical science · 2023
   Article
2. The Role of Apoptin in Chicken Anemia Virus Replication.Pathogens (Basel, Switzerland) · 2020
   Review
3. Apoptosis Triggered by ORF3 Proteins of theFrontiers in cellular and infection microbiology · 2020
   Review
4. Apoptin as a Tumor-Specific Therapeutic Agent: Current Perspective on Mechanism of Action and Delivery Systems.Frontiers in cell and developmental biology · 2020
   Review
5. Cancer Treatment Goes Viral: Using Viral Proteins to Induce Tumour-Specific Cell Death.Cancers · 2019
   Review
6. A truncated apoptin protein variant selectively kills cancer cells.Investigational new drugs · 2017
   Article
7. C-terminal region of apoptin affects chicken anemia virus replication and virulence.Virology journal · 2017
   Article
8. Viral genes as oncolytic agents for cancer therapy.Cellular and molecular life sciences : CMLS · 2015
   Review
9. Enhanced tumour cell nuclear targeting in a tumour progression model.BMC cancer · 2015
   Article
10. Human-gyrovirus-Apoptin triggers mitochondrial death pathway--Nur77 is required for apoptosis triggering.Neoplasia (New York, N.Y.) · 2014
    Article
11. Apoptin nucleocytoplasmic shuttling is required for cell type-specific localization, apoptosis, and recruitment of the anaphase-promoting complex/cyclosome to PML bodies.Journal of virology · 2006
    Article

Corrections and comments

• Comment on
  Apoptin/VP3 contains a concentration-dependent nuclear localization signal (NLS), not a tumorigenic selective NLS.2004

Authors and funding

7 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as