Evidence map›Paper›PMID 15611184›Full record

SynthesisGenetics2004

Genetic architecture of flowering time in maize as inferred from quantitative trait loci meta-analysis and synteny conservation with the rice genome.

Fabien Chardon, Bérangère Virlon, Laurence Moreau, Matthieu Falque, Johann Joets, Laurent Decousset, Alain Murigneux, Alain Charcosset

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 174 papers, 20 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
174citing papers in PubMed, 20 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

174 citing papers in PubMed, 20 syntheses or guidelines pooled it, 397 citations in OpenAlex.

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  4. Meta-analysis of seed weight QTLome using a consensus and highly dense genetic map in Brassica napus L.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023
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  7. Meta-QTLs for multiple disease resistance involving three rusts in common wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
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  8. Pinpointing genomic regions associated with root system architecture in rice through an integrative meta-analysis approach.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
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114 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Fabien ChardonINRA/INA-PG/UPS/CNRS, Station de Génétique Végétale, 91190 Gif-sur-Yvette, France.
Bérangère Virlon
Laurence Moreau
Matthieu Falque
Johann Joets
Laurent Decousset
Alain Murigneux
Alain Charcosset
Centre National de la Recherche Scientifique · FRBiogemma (France) · FRCentre de Génétique Moléculaire · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic architecture of flowering time in maize was addressed by synthesizing a total of 313 quantitative trait loci (QTL) available for this trait. These were analyzed first with an overview statistic that highlighted regions of key importance and then with a meta-analysis method that yielded a synthetic genetic model with 62 consensus QTL. Six of these displayed a major effect. Meta-analysis led in this case to a twofold increase in the precision in QTL position estimation, when compared to the most precise initial QTL position within the corresponding region. The 62 consensus QTL were compared first to the positions of the few flowering-time candidate genes that have been mapped in maize. We then projected rice candidate genes onto the maize genome using a synteny conservation approach based on comparative mapping between the maize genetic map and japonica rice physical map. This yielded 19 associations between maize QTL and genes involved in flowering time in rice and in Arabidopsis. Results suggest that the combination of meta-analysis within a species of interest and synteny-based projections from a related model plant can be an efficient strategy for identifying new candidate genes for trait variation.

Indexed as

SyntenyChromosome MappingFlowering TopsGenetic MarkersOryzaQuantitative Trait LociZea maysGenetic Markers

Identifiers

PMID15611184
PMCPMC1448716
OpenAlexW2165278024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.