ArticleGenetics2004
The role of natural selection in genetic differentiation of worldwide populations of Drosophila ananassae.
Article in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- The role of recombination landscape in species hybridisation and speciation.Frontiers in plant science · 2023Review
- Molecular population genetics of the NADPH cytochrome P450 reductase (CPR) gene in Anopheles minimus.Genetica · 2014Article
- Recombination rate variation and speciation: theoretical predictions and empirical results from rabbits and mice.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2012Review
- Article
- Genetic hitchhiking versus background selection: the controversy and its implications.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010Review
- Species-wide genetic variation and demographic history of Drosophila sechellia, a species lacking population structure.Genetics · 2009Article
- Development of nuclear DNA markers for evolutionary studies in Plasmodium falciparum.Journal of genetics · 2007Article
- The genetic structure of Drosophila ananassae populations from Asia, Australia and Samoa.Genetics · 2007Article
- The adaptive hypothesis of clinal variation revisited: single-locus clines as a result of spatially restricted gene flow.Genetics · 2006Review
- DNA sequence polymorphism and divergence at the erect wing and suppressor of sable loci of Drosophila melanogaster and D. simulans.Genetics · 2005Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main evolutionary forces leading to genetic differentiation between populations are generally considered to be natural selection, random genetic drift, and limited migration. However, little empirical evidence exists to help explain the extent, mechanism, and relative role of these forces. In this study, we make use of the differential migration behavior of genes located in regions of low and high recombination to infer the role and demographic distribution of natural selection in Drosophila ananassae. Sequence data were obtained from 13 populations, representing almost the entire range of cosmopolitan D. ananassae. The pattern of variation at a 5.1-kb fragment of the furrowed gene, located in a region of very low recombination, appears strikingly different from that of 10 noncoding DNA fragments (introns) in regions of normal to high recombination. Most interestingly, two main haplotypes are present at furrowed, one being fixed in northern populations and the other being fixed or in high frequency in more southern populations. A cline in the frequency of one of these haplotypes occurs in parallel latitudinal transects. Taken together, significant clinal variation and a test against alternative models of natural selection provide evidence of two independent selective sweeps restricted to specific regions of the species range.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.