Evidence map›Paper›PMID 15610695›Full record

ReviewCurrent urology reports2005

Chemotherapies and immunotherapies for metastatic kidney cancer.

Yoo-Joung Ko, Michael B Atkins

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current urology reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Yoo-Joung KoDivision of Medical Oncology/Hematology, Sunnybrook and Women's College Health Sciences Centre, 2075 Bayview Avenue, T-Wing, Toronto, Ontario, Canada. yoo-joung.ko@sw.ca
Michael B Atkins
Beth Israel Deaconess Medical Center · USSunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most patients who develop kidney cancer are effectively treated with a radical nephrectomy; however, for those patients who present with or develop metastatic disease, the therapeutic options are limited. Interferon and interleukin-2 remain the standard therapies. Several studies have identified the optimal doses and schedules of these cytokines and groups of patients most likely to benefit from immunotherapy. Although cytotoxic chemotherapy continues to have a minor role in patients with clear cell renal carcinoma, it may become the treatment of choice for some patients with variant renal cancers. Novel agents targeting the vascular endothelial growth factor, its receptor, and other hypoxia-induced proteins are showing great promise and soon may expand the therapeutic options for patients with advanced kidney cancer.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsClinical Trials, Phase III as TopicFemaleHumansImmunosuppressive AgentsImmunotherapyInterferonsInterleukinsKidney NeoplasmsMaleNeoplasm StagingPrognosisRandomized Controlled Trials as TopicRisk AssessmentSurvival RateTreatment OutcomeImmunosuppressive AgentsInterferonsInterleukins

Identifiers

PMID15610695
OpenAlexW2013105338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.