ArticleNeurosurgical review2005
Surgical treatment for brain metastases: prognostic factors and survival in 177 patients.
Article in Neurosurgical review, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- Sodium fluorescein-guided resection of brain metastases: A needed approach or an option? A systematic review and meta-analysis.Acta neurochirurgica · 2024Pooled it
- Central nervous system cancers.Journal of the National Comprehensive Cancer Network : JNCCN · 2013Guideline
- Risk stratification for unfavorable outcome after resection of selected brain metastases in patients with multiple brain metastases.Journal of neuro-oncology · 2026Article
- Fractionated Gamma Knife Radiosurgery as a Primary Treatment for Large Brain Metastases.Journal of Korean medical science · 2025Article
- Article
- Surgical treatment of cerebellar metastases in elderly patients: A threshold that moves forward?World neurosurgery: X · 2023Article
- Recurrent brain metastases: the role of resection of in a comprehensive multidisciplinary treatment setting.BMC cancer · 2022Article
- Prediction of Short and Long Survival after Surgery for Breast Cancer Brain Metastases.Cancers · 2022Article
- Brain metastases: increasingly precision medicine-a narrative review.Annals of translational medicine · 2021Review
- Clinical characteristics and risk factors of perioperative outcomes in elderly patients with intracranial tumors.Neurosurgical review · 2021Article
- Supracerebellar infratentorial inverted subchoroidal approach to lateral ventricle lesions: Anatomical study and illustrative case.Surgical neurology international · 2021Article
- Neurosurgical management of patients with brain metastasis.Neurosurgical review · 2020Review
- Operative and peri-operative considerations in the management of brain metastasis.Cancer medicine · 2019Review
- Survival and prognostic factors in surgically treated brain metastases.Journal of neuro-oncology · 2019Article
- Sodium fluorescein-guided brain tumor surgery under the YELLOW-560-nm surgical microscope filter in pediatric age group: feasibility and preliminary results.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Safety of resident training in the microsurgical resection of intracranial tumors: Data from a prospective registry of complications and outcome.Scientific reports · 2019Article
- Application of fluorescein sodium in breast cancer brain-metastasis surgery.Cancer management and research · 2018Article
- [Crizotinib Treatment Combined with Resection and Whole-brain Radiation Therapy in A ROS1 Rearranged Lung Adenocarcinoma with Brain Metastasis: Case Report and Literature Review].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2016Article
- Methods and results of locoregional treatment of brain metastases in patients with non-small cell lung cancer.Contemporary oncology (Poznan, Poland) · 2016Review
- Lung cancer: Biology and treatment options.Biochimica et biophysica acta · 2015Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain metastases are an increasingly frequent complication of cancer. Advances in diagnosis and treatment have led to wider indications for surgery. We present a single-institution series of 177 patients and discuss our results with regard to the literature. Special focus is on patients with advanced age, multiple brain metastases, extracranial metastases, and brain metastasis recurrence. All patients underwent craniotomy for the resection of solid tumor brain metastases between 1994 and 2001 in our department. Perioperative morbidity and mortality as well as survival were evaluated. The median patient age was 59 years (range 32-86 years). In 177 patients, 348 brain metastases were detected, of which 68.0% were supratentorial and 32.0% were infratentorial. According to univariate analysis, the following parameters were significantly associated with prolonged patient survival: (1) age <70 years, (2) one to three intracranial metastases, (3) favorable postoperative performance, (4) resection of all intracranial lesions, and (5) recraniotomy for brain metastasis recurrence. In contrast, the presence of extracranial metastases, metachronous diagnosis, and solitary brain metastases had no influence on survival. As expected, younger age and limited number of brain metastases (up to three) are favorable prognostic factors. Remarkably, the presence of extracranial metastases had no influence on patient survival.
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