ArticleHistochemistry and cell biology2005
The novel protein PTPIP51 exhibits tissue- and cell-specific expression.
Article in Histochemistry and cell biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- RMD-3 and RMD-6 identified as new components of the MSP fibrous body complex inmicroPublication biology · 2025Article
- PTPIP51 regulates mouse cardiac ischemia/reperfusion through mediating the mitochondria-SR junction.Scientific reports · 2017Article
- VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis.Human molecular genetics · 2012Article
- Interaction of PTPIP51 with Tubulin, CGI-99 and Nuf2 During Cell Cycle Progression.Biomolecules · 2012Article
- Differentiation-dependent PTPIP51 expression in human skeletal muscle cell culture.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2009Article
- Protein tyrosine phosphatase interacting protein 51 (PTPIP51) mRNA expression and localization and its in vitro interacting partner protein tyrosine phosphatase 1B (PTP1B) in human placenta of the first, second, and third trimester.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2009Article
- The novel protein PTPIP51 is expressed in human keratinocyte carcinomas and their surrounding stroma.Journal of cellular and molecular medicine · 2008Article
- Expression of PTPIP51 during mouse eye development.Histochemistry and cell biology · 2008Article
- Recent progress in histochemistry.Histochemistry and cell biology · 2007Review
- Expression of the novel protein PTPIP51 in rat liver: an immunohistochemical study.Histochemistry and cell biology · 2007Article
- Use of suppression subtractive hybridization to identify genes regulated by ciliary neurotrophic factor in postnatal retinal explants.Molecular vision · 2007Article
- The histochemistry and cell biology vade mecum: a review of 2005-2006.Histochemistry and cell biology · 2006Review
- Recent progress in histochemistry and cell biology: the state of the art 2005.Histochemistry and cell biology · 2005Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The expression patterns of both mRNA and protein of the novel protein tyrosine phosphatase interacting protein 51 (PTPIP51) were studied in various organs by in situ hybridization, immunoblotting, and immunocytochemistry. The protein was found in all mammalian species investigated: guinea pig, rat, mouse, pig, and human. The presence of the protein was, however, restricted to specific organs. High levels of PTPIP51 were found in epidermis and seminiferous epithelium. The expression appears to be associated with distinct stages of differentiation. While basal cells in the epidermis and spermatogonia showed no perceptible amount of PTPIP51, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibited high expression. In skeletal muscle, the presence of PTPIP51 was restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, the protein was associated with the microtubular structures responsible for ciliary movement. Furthermore, specific structures of the central nervous system, for example, neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system showed a distinct staining pattern with the antibody to PTPIP51. Our data suggest that PTPIP51 might be involved in the regulation of cellular processes associated with differentiation, movement, or cytoskeletal organization.
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Registered trials
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